Caries prevalence remains high throughout the world, with the burden of disease
increasingly affecting older and socially disadvantaged groups in Western cultures. If left …

Dental caries is a common disease that not only destroys the rigid structure of the teeth but
also causes pulp necrosis in severe cases. Once pulp necrosis has occurred, the most …

This opinion-led review paper highlights the need for novel translational research in vital-
pulp-treatment (VPT), but also discusses the challenges in translating evidence to clinics …

A thorough understanding of the biology of the dentine–pulp complex is essential to
underpin new treatment approaches and maximize clinical impact for regenerative …

Abstract Purpose of Review To summarize current views on the role and therapeutic
potential of growth factors (GFs) within endodontic cell homing. Recent Findings Cell …

Macrophages are immune cells with high plasticity that perform many functions related to
tissue injury and repair. They are generally categorized as 2 functional phenotypes: M1 …

Abstract Dental Pulp Stem Cells (DPSCs) offer great potential in regenerative medicine.
Odontoblasts are naturally occurring cells that are responsible for constructing dentin for …

To maximize the potential for clinical success of regenerative endodontic treatments, an in‐
depth understanding of the biology of the dentine‐pulp complex and its innate defence and …

Maintaining healthy pulp tissue and preventing apical periodontitis form the basis of
minimally invasive, biologically based vital pulp treatment (VPT). Although the dental pulp …

Съвременната медицина цели минимална намеса в биологичната цялост на
организма. За целта се използват съвременни средства за ранна диагностика на …