An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

The consumption of Western-type calorically rich diets combined with chronic overnutrition
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …

Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

The global population is aging and the prevalence of age-related diseases, such as
Alzheimer's disease and vascular dementia is increasing. Understanding functional …

Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …

The steady rise in the prevalence of obesity has been fostered by modern environments that
reduce energy expenditure and encourage consumption of 'western'-style diets high in fat …

Background: Evidence has revealed an association between familial hypercholesterolemia
and cognitive impairment. In this regard, a connection between cognitive deficits and …

Cardiac autonomic neuropathy (CAN) is one of the earliest complications of type 2 diabetes
(T2D), presenting a silent cause of cardiovascular morbidity and mortality. Recent research …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to
dementia and patient death. AD is characterized by intracellular neurofibrillary tangles …

Familial hypercholesterolemia (FH) is a metabolic condition caused mainly by a mutation in
the low-density lipoprotein (LDL) receptor gene (LDLR), which is highly prevalent in the …