The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

Restoring joint homeostasis is crucial for relieving osteoarthritis (OA). Current strategies are
limited to unilateral efforts in joint lubrication, inhibition of inflammation, free radicals …

Osteoarthritis (OA), as a chronic degenerative joint disorder, has seriously affected the life
quality of patients. Despite lots of drug treatment strategies that have been studied, the …

Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Osteoarthritis (OA) is a progressive chronic inflammation that leads to cartilage
degeneration. OA Patients are commonly given pharmacological treatment, but the available …

The high density structure of cartilage matrix negative charge seriously hinders the
penetration and enrichment of drugs/genes into cartilage tissue. In this study …

The osteoarthritis (OA) symptoms cannot be fully remedied by using only a single functional
component because of its complex pathogenesis. Herein, a MnO 2 nanozyme-encapsulated …

Objective To review the current state of pharmaceutical treatment recommendations for the
management of osteoarthritis. Method A narrative review was drafted to describe treatment …

Osteoarthritis (OA) is a low‐grade inflammatory and progressive joint disease, and its
progression is closely associated with an imbalance in M1/M2 synovial macrophages …