GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury

CR Brightwell, CM Latham, AR Keeble, NT Thomas… - Science …, 2023 - science.org
Musculoskeletal disorders contribute substantially to worldwide disability. Anterior cruciate
ligament (ACL) tears result in unresolved muscle weakness and posttraumatic osteoarthritis …

Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage

CM Latham, PJ Balawender, NT Thomas… - Free Radical Biology …, 2024 - Elsevier
Oxidative stress has been implicated in the etiology of skeletal muscle weakness following
joint injury. We investigated longitudinal patient muscle samples following knee injury …

[HTML][HTML] Vitamin D status associates with skeletal muscle loss after anterior cruciate ligament reconstruction

Y Wen, CM Latham, AN Moore, NT Thomas… - JCI insight, 2023 - ncbi.nlm.nih.gov
BACKGROUND Although 25-hydroxyvitamin D [25 (OH) D] concentrations of 30 ng/mL or
higher are known to reduce injury risk and boost strength, the influence on anterior cruciate …

Blood Flow Restriction Training in the Young Athlete

AP Weaver, Z Dunkle, N Giampetruzzi, J Prue… - HSS Journal …, 2024 - journals.sagepub.com
Blood flow restriction training (BFRT) is increasing in popularity in the rehabilitation setting
due to its believed impact on mitigating muscle atrophy, maintaining muscle mass and …

[HTML][HTML] Quadriceps muscle atrophy after non-invasive anterior cruciate ligament injury: evidence linking to autophagy and mitophagy

SG Noh, A Ahn, SM Davi, LK Lepley… - Frontiers in Physiology, 2024 - frontiersin.org
Introduction: Anterior cruciate ligament (ACL) injury is frequently accompanied by
quadriceps muscle atrophy, a process closely linked to mitochondrial health and …

Muscle Fiber Cross-Sectional Area Is Associated With Quadriceps Strength and Rate of Torque Development After ACL Injury

MC Graham, KL Thompson, GS Hawk… - The Journal of …, 2024 - journals.lww.com
Abstract Graham, MC, Thompson, KL, Hawk, GS, Fry, CS, and Noehren, B. Muscle fiber
cross-sectional area is associated with quadriceps strength and rate of torque development …

Skeletal muscle architecture and aging: A comparison of ultrasound techniques and an assessment of intrarater reliability

AC D'Lugos, NJ Skotak, JJ Faris… - Clinical Physiology …, 2024 - Wiley Online Library
Objective To assess intrarater reliability of ultrasound‐determined measurements of skeletal
muscle characteristics across different measurement outcomes, imaging techniques, and …

[HTML][HTML] Explosive strength and stretch-shortening-cycle capacity during ACL rehabilitation

MJ Jordan, P Aagaard, C Bishop, Z McClean… - Aspetar Sports …, 2023 - library.wur.nl
Human skeletal muscles are biological motors that drive movement and function, in turn,
causing functional capacity to be highly dependent on our muscles' strength capacity …