How do cells perceive time? Do cells use temporal information to regulate the production/
degradation of their enzymes, membranes, and organelles? Does controlling biological time …

While we have a solid understanding of the cell biological and biochemical control aspects
of the eukaryotic cell growth and division process, much less is known about the metabolic …

Networks of interacting molecules organize topology, amount, and timing of biological
functions. Systems biology concepts required to pin down 'network motifs' or 'design …

This study was conducted to investigate epigenetic landscape across multiple species and
identify transcription factors (TFs) and their roles in controlling cell fate decision events …

In the budding yeast Saccharomyces cerevisiae, transcription factors (TFs) regulate the
periodic expression of many genes during the cell cycle, including gene products required …

Cells vary in volume throughout their life cycle and in many other circumstances, while their
genome remains identical. Hence, the RNA production factory must adapt to changing …

Modeling biological systems holds great promise for speeding up the rate of discovery in
systems biology by predicting experimental outcomes and suggesting targeted …

Molecular signal transduction networks, which conduct transcription at the G1 to S phase
transition of the eukaryotic cell division cycle have been identified in diverse taxa from …

Experimental time series provide an informative window into the underlying dynamical
system, and the timing of the extrema of a time series (or its derivative) contains information …

Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are
controlled by a relatively small “core” network of transcription factors and post-translational …