Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina
S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
Viral infections and pathogenesis of glaucoma: a comprehensive review
F Ahmad, N Deshmukh, A Webel… - Clinical Microbiology …, 2023 - Am Soc Microbiol
Glaucoma is a leading cause of irreversible blindness worldwide, caused by the gradual
degeneration of retinal ganglion cells and their axons. While glaucoma is primarily …
degeneration of retinal ganglion cells and their axons. While glaucoma is primarily …
Ocular disease therapeutics: design and delivery of drugs for diseases of the eye
The ocular drug discovery field has evidenced significant advancement in the past decade.
The FDA approvals of Rhopressa, Vyzulta, and Roclatan for glaucoma, Brolucizumab for wet …
The FDA approvals of Rhopressa, Vyzulta, and Roclatan for glaucoma, Brolucizumab for wet …
Exosome-based crosstalk in glaucoma pathogenesis: a focus on oxidative stress and neuroinflammation
L Wang, X Wei - Frontiers in Immunology, 2023 - frontiersin.org
Exosomes are membrane-bound tiny particles that are released by all live cells that contain
multiple signal molecules and extensively participate in numerous normal physical activities …
multiple signal molecules and extensively participate in numerous normal physical activities …
T cell-mediated autoimmunity in glaucoma neurodegeneration
L Wang, X Wei - Frontiers in Immunology, 2021 - frontiersin.org
Glaucoma as the leading neurodegenerative disease leads to blindness in 3.6 million
people aged 50 years and older worldwide. For many decades, glaucoma therapy has …
people aged 50 years and older worldwide. For many decades, glaucoma therapy has …
Melatonin in retinal physiology and pathology: the case of age‐related macular degeneration
J Blasiak, RJ Reiter… - Oxidative medicine and …, 2016 - Wiley Online Library
Melatonin, an indoleamine, is synthesized mainly in the pineal gland in a circadian fashion,
but it is produced in many other organs, including the retina, which seems to be especially …
but it is produced in many other organs, including the retina, which seems to be especially …
Generation of a transplantable population of human iPSC-derived retinal ganglion cells
O Rabesandratana, A Chaffiol, A Mialot… - Frontiers in Cell and …, 2020 - frontiersin.org
Optic neuropathies are a major cause of visual impairment due to retinal ganglion cell
(RGC) degeneration. Human induced-pluripotent stem cells (iPSCs) represent a powerful …
(RGC) degeneration. Human induced-pluripotent stem cells (iPSCs) represent a powerful …
Characterizing the “POAGome”: A bioinformatics-driven approach to primary open-angle glaucoma
ID Danford, LD Verkuil, DJ Choi, DW Collins… - Progress in retinal and …, 2017 - Elsevier
Primary open-angle glaucoma (POAG) is a genetically, physiologically, and phenotypically
complex neurodegenerative disorder. This study addressed the expanding collection of …
complex neurodegenerative disorder. This study addressed the expanding collection of …
Novel therapies for glaucoma: a patent review (2013-2019)
P Guglielmi, S Carradori, C Campestre… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Glaucoma is one of the main leading causes of irreversible blindness in the
world. The treatment of this disease relies on the use of drugs able to reduce/control the …
world. The treatment of this disease relies on the use of drugs able to reduce/control the …
Detection of glaucoma based on cup-to-disc ratio using fundus images
Glaucoma is a permanent damage of optic nerves which cause of partial or complete visual
loss. This work presents a glaucoma detection scheme by measuring CDR from fundus …
loss. This work presents a glaucoma detection scheme by measuring CDR from fundus …