Background Antibiotic stewardship programmes have been shown to reduce antibiotic use
and hospital costs. We aimed to evaluate evidence of the effect of antibiotic stewardship on …

Antibiotics have transformed medicine, saving millions of lives since they were first used to
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …

BACKGROUND Antibiotics are among the most important tools in medicine, but their efficacy
is threatened by the evolution of resistance. Since the earliest days of antibiotics, resistance …

Human infections by the bacterial pathogen Salmonella enterica represent major disease
burdens worldwide. This highly ubiquitous species consists of more than 2600 different …

The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs
worldwide threaten adequate antibiotic coverage of infected patients in this environment …

Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because
MDR infections are often significantly harder and more expensive to treat, they represent a …

Background: Antibiotic resistance is a threat to the effective prevention and treatment of an
ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. Sources …

The rapid rise of antibiotic resistance, combined with the increasing cost and difficulties to
develop new antibiotics, calls for treatment strategies that enable more sustainable antibiotic …

Antimicrobial peptides (AMPs) have been proposed as a promising class of new
antimicrobials partly because they are less susceptible to bacterial resistance evolution. This …

Since the concept of antimicrobial stewardship was introduced by McGowan and Finland 1
and others in the 1970s, stewardship programs have evolved from costcontainment …