Tfos dews ii pathophysiology report
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …
[HTML][HTML] The diagnosis of limbal stem cell deficiency
Q Le, J Xu, SX Deng - The ocular surface, 2018 - Elsevier
Limbal stem cells (LSCs) maintain the normal homeostasis and wound healing of corneal
epithelium. Limbal stem cell deficiency (LSCD) is a pathologic condition that results from the …
epithelium. Limbal stem cell deficiency (LSCD) is a pathologic condition that results from the …
Human limbal epithelial stem cell regulation, bioengineering and function
C Bonnet, S González, JAS Roberts… - Progress in retinal and …, 2021 - Elsevier
The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions
L Latta, FC Figueiredo, R Ashery-Padan, JM Collinson… - The ocular …, 2021 - Elsevier
Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …
13 years of cultured limbal epithelial cell therapy: a review of the outcomes
O Baylis, F Figueiredo, C Henein… - Journal of cellular …, 2011 - Wiley Online Library
The cornea is the clear tissue at the front of the eye which enables the transmission of light
to the retina for normal vision. The surface of the cornea is composed of an epithelium which …
to the retina for normal vision. The surface of the cornea is composed of an epithelium which …
Tracing the fate of limbal epithelial progenitor cells in the murine cornea
N Di Girolamo, S Bobba, V Raviraj, NC Delic… - Stem …, 2015 - academic.oup.com
Stem cell (SC) division, deployment, and differentiation are processes that contribute to
corneal epithelial renewal. Until now studying the destiny of these cells in a living mammal …
corneal epithelial renewal. Until now studying the destiny of these cells in a living mammal …
[HTML][HTML] Limbal stem cells: Central concepts of corneal epithelial homeostasis
JJ Yoon, S Ismail, T Sherwin - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
A strong cohort of evidence exists that supports the localisation of corneal stem cells at the
limbus. The distinguishing characteristics of limbal cells as stem cells include slow cycling …
limbus. The distinguishing characteristics of limbal cells as stem cells include slow cycling …
Chemical eye injury: pathophysiology, assessment and management
Chemical eye injury (CEI) is an acute emergency which can threaten sight and life. These
commonly occur at home or the workplace with the former being generally mild and the latter …
commonly occur at home or the workplace with the former being generally mild and the latter …
Concise review: limbal stem cell deficiency, dysfunction, and distress
S Ahmad - Stem cells translational medicine, 2012 - academic.oup.com
The cornea is the clear tissue at the front of the eye that transmits light to the retina at the
back of the eye. The cornea is covered by an epithelium and surrounded by a narrow band …
back of the eye. The cornea is covered by an epithelium and surrounded by a narrow band …
Corneal-committed cells restore the stem cell pool and tissue boundary following injury
W Nasser, A Amitai-Lange, D Soteriou, R Hanna… - Cell reports, 2018 - cell.com
During morphogenesis, preserving tissue boundaries is essential for cell fate regulation.
While embryonic tissues possess high plasticity and repair ability, the questions of whether …
While embryonic tissues possess high plasticity and repair ability, the questions of whether …