Adverse prenatal exposures and fetal brain development: insights from advanced fetal magnetic resonance imaging

J De Asis-Cruz, N Andescavage… - Biological Psychiatry …, 2022 - Elsevier
Converging evidence from clinical and preclinical studies suggests that fetal vulnerability to
adverse prenatal exposures increases the risk for neuropsychiatric diseases such as autism …

Murine models for the study of fetal alcohol spectrum disorders: An overview

L Almeida, V Andreu-Fernández… - Frontiers in …, 2020 - frontiersin.org
Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and
neurological impairments collectively known as fetal alcohol spectrum disorder. The …

Alcohol metabolism contributes to brain histone acetylation

P Mews, G Egervari, R Nativio, S Sidoli, G Donahue… - Nature, 2019 - nature.com
Emerging evidence suggests that epigenetic regulation is dependent on metabolic state,
and implicates specific metabolic factors in neural functions that drive behaviour. In neurons …

Impact of alcohol exposure on neural development and network formation in human cortical organoids

JW Adams, PD Negraes, J Truong, T Tran… - Molecular …, 2023 - nature.com
Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and
leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD) …

Curcumin treatment attenuates alcohol-induced alterations in a mouse model of foetal alcohol spectrum disorders

L Cantacorps, S Montagud-Romero… - Progress in Neuro …, 2020 - Elsevier
Alcohol exposure during development produces physical and mental abnormalities in the
foetus that result in long-term molecular adjustments in the brain, which could underlie the …

[HTML][HTML] The impact of early-life environment on absence epilepsy and neuropsychiatric comorbidities

K Sarkisova, G van Luijtelaar - IBRO Neuroscience Reports, 2022 - Elsevier
This review discusses the long-term effects of early-life environment on epileptogenesis,
epilepsy, and neuropsychiatric comorbidities with an emphasis on the absence epilepsy …

Fetal alcohol spectrum disorders awareness in health professionals: Implications for psychiatry

MP Messina, A D'Angelo, G Battagliese… - Rivista di …, 2020 - iris.uniroma1.it
Abstract Fetal Alcohol Spectrum Disorders (FASD) are a plethora of malformative conditions
leading to mental retardation that affect newborns and children who have been exposed to …

Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and …

KR LeFort, W Rungratanawanich, BJ Song - Cellular and Molecular Life …, 2024 - Springer
This review provides an update on recent findings from basic, translational, and clinical
studies on the molecular mechanisms of mitochondrial dysfunction and apoptosis of …

[HTML][HTML] Integrated serum and liver metabolomics decipher the hepatoprotective mechanisms of mangiferin sodium salt through modulating alcohol metabolism on …

Z Li, Z Pu, Y Gao, M Zhou, Z Zhang, P Xiao, J Chen… - Food Bioscience, 2024 - Elsevier
The natural xanthone derivative mangiferin (MG) has recently been identified as possessing
hepatoprotective potential. Yet, its natural form suffers from low bioavailability, and until now …

[HTML][HTML] Epigenetic changes in inflammatory genes and the protective effect of cooked rhubarb on pancreatic tissue of rats with chronic alcohol exposure

X Zhao, S Zhu, J Li, D Long, M Wan, W Tang - Biomedicine & …, 2022 - Elsevier
Chronic alcohol consumption, which is observed worldwide, can damage pancreatic tissue
and promote pancreatitis. Rhubarb is a widely used traditional Chinese herbal medicine for …