Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models

A Stewart, N Wu, J Cachat, P Hart, S Gaikwad… - Progress in Neuro …, 2011 - Elsevier
Zebrafish (Danio rerio) are becoming increasingly popular in neurobehavioral research.
Here, we summarize recent data on behavioral responses of adult zebrafish to a wide …

Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra

MS de Abreu, ACVV Giacomini, KA Demin… - Pharmacology …, 2021 - Elsevier
Anxiety is the most prevalent brain disorder and a common cause of human disability.
Animal models are critical for understanding anxiety pathogenesis and its pharmacotherapy …

Imbalance of approach and avoidance: the yin and yang of anxiety disorders

MB Stein, MP Paulus - Biological psychiatry, 2009 - biologicalpsychiatryjournal.com
Two interesting articles from Harvard University investiga-tors in this issue of Biological
Psychiatry challenge us to reconsider and rethink the complexities of the underlying …

Rapid well-plate assays for motor and social behaviors in larval zebrafish

Q Shen, L Truong, MT Simonich, C Huang… - Behavioural brain …, 2020 - Elsevier
Behavior phenotypes are a powerful means of uncovering subtle xenobiotic chemical
impacts on vertebrate nervous system development. Rodents manifest complex and …

α7-Containing nicotinic acetylcholine receptors on interneurons of the basolateral amygdala and their role in the regulation of the network excitability

VI Pidoplichko, EM Prager… - Journal of …, 2013 - journals.physiology.org
The basolateral amygdala (BLA) plays a key role in fear-related learning and memory, in the
modulation of cognitive functions, and in the overall regulation of emotional behavior …

Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior

JR Turner, LM Castellano, JA Blendy - Journal of Pharmacology and …, 2010 - ASPET
Clinical and preclinical studies suggest that nicotinic acetylcholine receptors are involved in
affective disorders; therefore, the potential therapeutic value of nicotinic partial agonists as …

[HTML][HTML] Anxiolytic effects of fluoxetine and nicotine exposure on exploratory behavior in zebrafish

ML Singer, K Oreschak, Z Rhinehart, BD Robison - PeerJ, 2016 - peerj.com
Zebrafish (Danio rerio) have emerged as a popular model for studying the pharmacology
and behavior of anxiety. While there have been numerous studies documenting the …

Bilateral fronto-parietal integrity in young chronic cigarette smokers: a diffusion tensor imaging study

Y Liao, J Tang, Q Deng, Y Deng, T Luo, X Wang… - PloS one, 2011 - journals.plos.org
Background Cigarette smoking continues to be the leading cause of preventable morbidity
and mortality in China and other countries. Previous studies have demonstrated gray matter …

Anxiety sensitivity and negative urgency: A pathway to negative reinforcement-related smoking expectancies

CR Guillot, RD Pang, AM Leventhal - Journal of addiction …, 2014 - journals.lww.com
Objectives: Anxiety sensitivity—fear of anxiety symptoms—may increase motivation to
smoke by influencing the development of cognitive expectations regarding smoking's …

Cognitive enhancers for facilitating drug cue extinction: insights from animal models

BÁN Dhonnchadha, KM Kantak - Pharmacology Biochemistry and Behavior, 2011 - Elsevier
Given the success of cue exposure (extinction) therapy combined with a cognitive enhancer
for reducing anxiety, it is anticipated that this approach will prove more efficacious than …