Endothelial dysfunction and vascular disease

PM Vanhoutte, H Shimokawa, EHC Tang… - Acta …, 2009 - Wiley Online Library
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

The endothelium, Part I: Multiple functions of the endothelial cells--focus on endothelium-derived vasoactive mediators

M Félétou - 2011 - books.google.com
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence?

I Bernatova - BioMed research international, 2014 - Wiley Online Library
Hypertension is a risk factor for other cardiovascular diseases and endothelial dysfunction
was found in humans as well as in various commonly employed animal experimental …

Rodent models of hypertension

HA Jama, RR Muralitharan, C Xu… - British Journal of …, 2022 - Wiley Online Library
Elevated blood pressure (BP), or hypertension, is the main risk factor for cardiovascular
disease. As a multifactorial and systemic disease that involves multiple organs and systems …

L-NAME in the cardiovascular system—nitric oxide synthase activator?

J Kopincová, A Púzserová, I Bernátová - Pharmacological Reports, 2012 - Springer
L-arginine analogues are widely used inhibitors of nitric oxide synthase (NOS) activity both
in vitro and in vivo, with N ω-nitro-L-arginine methyl ester (L-NAME) being at the head. On …

Ferulic acid improves cardiovascular and kidney structure and function in hypertensive rats

MA Alam, C Sernia, L Brown - Journal of Cardiovascular …, 2013 - journals.lww.com
Ferulic acid is a simple phenolic acid commonly present in cereals. In this study, changes in
heart and kidney structure and function were measured in young N ω-nitro-L-arginine methyl …

[PDF][PDF] Participation of nitric oxide in different models of experimental hypertension.

J Török - Physiological research, 2008 - biomed.cas.cz
Participation of Nitric Oxide in Different Models of Experimental Hypertension Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2008 …

[PDF][PDF] Blood pressure regulation in stress: focus on nitric oxide-dependent mechanisms

A Puzserova, I Bernatova - Physiol Res, 2016 - paulwulleman.be
Blood Pressure Regulation in Stress: Focus on Nitric Oxide-Dependent Mechanisms Page 1
PHYSIOLOGICAL RESEARCH ISSN 0862-8408(print) ISSN 1802-9973(online) © 2016 Institute …

PPAR-γ agonist, pioglitazone, reduced oxidative and endoplasmic reticulum stress associated with L-NAME-induced hypertension in rats

E Soliman, SF Behairy, NN El-Maraghy, SM Elshazly - Life Sciences, 2019 - Elsevier
Peroxisome proliferator-activated receptor γ (PPAR-γ) agonist, pioglitazone, is used
clinically to improve the glycemic state in patients with type-2 diabetes mellitus. Independent …

Increased NOS coupling by the metabolite tetrahydrobiopterin (BH4) reduces preeclampsia/IUGR consequences

L Chatre, A Ducat, FT Spradley, AC Palei, C Chéreau… - Redox Biology, 2022 - Elsevier
Preeclampsia (PE) is a high-prevalence pregnancy disease characterized by placental
insufficiency, gestational hypertension, and proteinuria. Overexpression of the A isoform of …