Prone positioning was first proposed in the 1970s as a method to improve gas exchange in
ARDS. Subsequent observations of dramatic improvement in oxygenation with simple …

Optimizing gas exchange, avoiding lung injury, and preserving respiratory muscle strength
and endurance are vital therapeutic objectives for managing acute lung injury. Accordingly …

The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …

Every year, more information accumulates about the possibility of treating patients with acute
lung injury or acute respiratory distress syndrome with specially designed mechanical …

Non-invasive high-frequency oscillatory (NHFOV) and percussive (NHFPV) ventilation
represent two non-conventional techniques that may be useful in selected neonatal patients …

The explanation for prone and supine differences in tissue density and pleural pressure
gradients in the healthy lung has been inferred from several studies as compression of …

Purpose To evaluate lung water density at three different levels of lung inflation in normal
lungs using a fast gradient echo sequence developed for rapid imaging. Materials and …

Recent evidence suggests that endothelial dysfunction and pathology of pulmonary vascular
responses may serve as a precursor to smoking-associated emphysema. Although it is …

Background Bedside electrical impedance tomography could be useful to visualize evolving
pulmonary perfusion distributions when acute respiratory distress syndrome worsens or in …