Microbiome, probiotics and neurodegenerative diseases: deciphering the gut brain axis
The gut microbiota is essential to health and has recently become a target for live bacterial
cell biotherapies for various chronic diseases including metabolic syndrome, diabetes …
cell biotherapies for various chronic diseases including metabolic syndrome, diabetes …
Different cognitive frailty models and health-and cognitive-related outcomes in older age: from epidemiology to prevention
Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …
health-related events, includes physical, cognitive, and psychosocial domains or …
Neuropeptides and microglial activation in inflammation, pain, and neurodegenerative diseases
L Carniglia, D Ramírez, D Durand… - Mediators of …, 2017 - Wiley Online Library
Microglial cells are responsible for immune surveillance within the CNS. They respond to
noxious stimuli by releasing inflammatory mediators and mounting an effective inflammatory …
noxious stimuli by releasing inflammatory mediators and mounting an effective inflammatory …
Blood biomarkers for traumatic brain injury: a quantitative assessment of diagnostic and prognostic accuracy
Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …
Implications of the gut microbiome in Parkinson's disease
Parkinson's disease is a common neurodegenerative disorder that presents with nonmotor
and motor symptoms. The nonmotor manifestations of Parkinson's disease often begin years …
and motor symptoms. The nonmotor manifestations of Parkinson's disease often begin years …
Therapeutic potential of targeting the ghrelin pathway
Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …
Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?
G Curia, C Lucchi, J Vinet, F Gualtieri… - Current medicinal …, 2014 - ingentaconnect.com
Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly
caused by a primary brain injury that occurred a long time before the appearance of …
caused by a primary brain injury that occurred a long time before the appearance of …
[HTML][HTML] Cognitive aspects of frailty: mechanisms behind the link between frailty and cognitive impairment
M Halil, MC Kizilarslanoglu, ME Kuyumcu… - The Journal of nutrition …, 2015 - Elsevier
Whereas physical impairment is the main hallmark of frailty, evidence suggests that other
dimensions, such as psychological, cognitive and social factors also contribute to this …
dimensions, such as psychological, cognitive and social factors also contribute to this …
Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder
Alcohol use disorder (AUD) is a leading cause of morbidity and mortality worldwide.
However, treatment options, including pharmacotherapies, are limited in number and …
However, treatment options, including pharmacotherapies, are limited in number and …
[HTML][HTML] Understanding the physiological links between physical frailty and cognitive decline
Declines in both physical and cognitive function are associated with increasing age.
Understanding the physiological link between physical frailty and cognitive decline may …
Understanding the physiological link between physical frailty and cognitive decline may …