[HTML][HTML] Using a Failing Human Ventricular Cardiomyocyte Model to Re-Evaluate Ca2+ Cycling, Voltage Dependence, and Spark Characteristics
Previous studies have observed alterations in excitation–contraction (EC) coupling during
end-stage heart failure that include action potential and calcium (Ca2+) transient …
end-stage heart failure that include action potential and calcium (Ca2+) transient …
Heart‐on‐a‐Miniscope: A Miniaturized Solution for Electrophysiological Drug Screening in Cardiac Organoids
P Tirgar, A Vikstrom, JMR Sepúlveda, LK Srivastava… - Small, 2024 - Wiley Online Library
Cardiovascular toxicity remains a primary concern in drug development, accounting for a
significant portion of post‐market drug withdrawals due to adverse reactions such as …
significant portion of post‐market drug withdrawals due to adverse reactions such as …
[HTML][HTML] Gain-of-Function and Loss-of-Function Mutations in the RyR2-Expressing Gene Are Responsible for the CPVT1-Related Arrhythmogenic Activities in the …
Mutations in the ryanodine receptor (RyR2) gene have been linked to arrhythmia and
possibly sudden cardiac death (SCD) during acute emotional stress, physical activities, or …
possibly sudden cardiac death (SCD) during acute emotional stress, physical activities, or …
[PDF][PDF] Journal of Population Therapeutics & Clinical Pharmacology
S Sohail, F Anjum, MI Khan, F Bibi, R Rehman, M Tariq - academia.edu
Objective: This review aims to reevaluate the molecular mechanisms of sarcoendoplasmic
reticulum Ca2+-dependent ATPase (SERC-A) in Alzheimer's disease and discuss the …
reticulum Ca2+-dependent ATPase (SERC-A) in Alzheimer's disease and discuss the …