Screening for fetal aneuploidies at 11 to 13 weeks
KH Nicolaides - Prenatal diagnosis, 2011 - Wiley Online Library
Effective screening for major aneuploidies can be provided in the first trimester of
pregnancy. Screening by a combination of fetal nuchal translucency and maternal serum …
pregnancy. Screening by a combination of fetal nuchal translucency and maternal serum …
Down's syndrome
NJ Roizen, D Patterson - The Lancet, 2003 - thelancet.com
The sequencing of chromosome 21 and the use of models of Down's syndrome in mice have
allowed us to relate genes and sets of genes to the neuropathogenesis of this syndrome …
allowed us to relate genes and sets of genes to the neuropathogenesis of this syndrome …
[图书][B] Overdiagnosed: making people sick in the pursuit of health
HG Welch, L Schwartz, S Woloshin - 2012 - books.google.com
An exposé on Big Pharma and the American healthcare system's zeal for excessive medical
testing, from a nationally recognized expert More screening doesn't lead to better health …
testing, from a nationally recognized expert More screening doesn't lead to better health …
Systematic reviews of diagnostic test accuracy
MMG Leeflang, JJ Deeks, C Gatsonis… - Annals of internal …, 2008 - acpjournals.org
More and more systematic reviews of diagnostic test accuracy studies are being published,
but they can be methodologically challenging. In this paper, the authors present some of the …
but they can be methodologically challenging. In this paper, the authors present some of the …
Meta‐analysis of second‐trimester markers for trisomy 21
M Agathokleous, P Chaveeva… - … in Obstetrics & …, 2013 - Wiley Online Library
Objective To summarize by meta‐analysis the accumulated data on the screening
performance of second‐trimester sonographic markers for fetal trisomy 21. Methods We …
performance of second‐trimester sonographic markers for fetal trisomy 21. Methods We …
Evidence of bias and variation in diagnostic accuracy studies
AWS Rutjes, JB Reitsma, M Di Nisio, N Smidt… - Cmaj, 2006 - Can Med Assoc
Background: Studies with methodologic shortcomings can overestimate the accuracy of a
medical test. We sought to determine and compare the direction and magnitude of the …
medical test. We sought to determine and compare the direction and magnitude of the …
Approaches to heterogeneity in meta‐analysis
DB Petitti - Statistics in medicine, 2001 - Wiley Online Library
This paper reviews publications from January 1999 to March 2001 on reproductive health
topics that were self‐identified as meta‐analysis or were indexed as meta‐analysis in …
topics that were self‐identified as meta‐analysis or were indexed as meta‐analysis in …
The effectiveness of diagnostic tests for the assessment of shoulder pain due to soft tissue disorders: a systematic review
J Dinnes, E Loveman, L McIntyre… - Health Technology …, 2003 - wrap.warwick.ac.uk
Objectives To evaluate the evidence for the effectiveness and cost-effectiveness of the
newer diagnostic imaging tests as an addition to clinical examination and patient history for …
newer diagnostic imaging tests as an addition to clinical examination and patient history for …
Isolated sonographic markers for detection of fetal Down syndrome in the second trimester of pregnancy.
DA Nyberg, VL Souter, A El-Bastawissi… - … of Ultrasound in …, 2001 - Wiley Online Library
To determine whether sonographic" markers" are associated with fetal Down syndrome
during the second trimester and to estimate the degree of risk of individual markers using …
during the second trimester and to estimate the degree of risk of individual markers using …
Empirical evidence of the importance of comparative studies of diagnostic test accuracy
Background: Systematic reviews that “compare” the accuracy of 2 or more tests often include
different sets of studies for each test. Purpose: To investigate the availability of direct …
different sets of studies for each test. Purpose: To investigate the availability of direct …