Allergic diseases are distributed worldwide and their risk factors and triggers vary according
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …

Asthma is an important health concern in Latin America (LA) where it is associated with
variable prevalence and disease burden between countries. High prevalence and morbidity …

The utility of genetically isolated populations (population isolates) in the mapping and
identification of genes is not only limited to the study of rare diseases; isolated populations …

Life history theory predicts that immunity should be plastic and reflect environmental
contexts. However, individual variation in immune investment may arise not just because of …

Food allergy (FA) is a complex disease of substantial public health concern; it affects w8% of
the pediatric population, and is the common cause of anaphylaxis in children, affecting up to …

Atopic dermatitis (AD), food allergy, allergic rhinitis, and asthma are common atopic
disorders of complex etiology. The frequently observed atopic march from early AD to …

This book examines why certain non-communicable diseases have become common, first in
affluent western populations, and increasingly, worldwide. It draws on an evolutionary …

This study was aimed to investigate the relationship between the interleukin‐4‐590C> T
gene polymorphism and the susceptibility to asthma by meta‐analysis. To explore the …

Mechanisms underlying the development of allergy are a complex interaction of genetic
susceptibility and environmental exposures. Identification of specific environmental factors …

This thesis explores the contribution of twin studies, particularly those studies originating
from the Danish Twin Registry, to the understanding of the aetiology of asthma. First, it is …