Pathophysiology of COVID-19-associated acute kidney injury

M Legrand, S Bell, L Forni, M Joannidis… - Nature Reviews …, 2021 - nature.com
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19,
kidney involvement is also common. Available evidence supports a number of potential …

Kidney injury in COVID-19: epidemiology, molecular mechanisms and potential therapeutic targets

JP Teixeira, S Barone, K Zahedi… - International Journal of …, 2022 - mdpi.com
As of December 2021, SARS-CoV-2 had caused over 250 million infections and 5 million
deaths worldwide. Furthermore, despite the development of highly effective vaccines, novel …

Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients

V Montiel, I Lobysheva, L Gerard, M Vermeersch… - …, 2022 - thelancet.com
Background SARS-CoV-2 targets endothelial cells through the angiotensin-converting
enzyme 2 receptor. The resulting endothelial injury induces widespread thrombosis and …

Alveolar, endothelial, and organ injury marker dynamics in severe COVID-19

DE Leisman, A Mehta, BT Thompson… - American journal of …, 2022 - atsjournals.org
Rationale: Alveolar and endothelial injury may be differentially associated with coronavirus
disease (COVID-19) severity over time. Objectives: To describe alveolar and endothelial …

The cerebellum and anxiety

PW Chin, GJ Augustine - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Although the cerebellum is traditionally known for its role in motor functions, recent evidence
points toward the additional involvement of the cerebellum in an array of non-motor …

COVID-19: A redox disease—What a stress pandemic can teach us about resilience and what we may learn from the reactive species interactome about its treatment

AF Cumpstey, AD Clark, J Santolini… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
causing coronavirus disease 2019 (COVID-19), affects every aspect of human life by …

Hyperviscosity syndrome in COVID-19 and related vaccines: exploring of uncertainties

HM Al-Kuraishy, AI Al-Gareeb, MM El-Bouseary… - Clinical and …, 2023 - Springer
Hyperviscosity syndrome (HVS) recently emerged as a complication of coronavirus disease
2019 (COVID-19) and COVID-19 vaccines. Therefore, the objectives of this critical review …

The systemic renin-angiotensin system in COVID-19

R Reindl-Schwaighofer, S Hödlmoser, O Domenig… - Scientific Reports, 2022 - nature.com
SARS-CoV-2 gains cell entry via angiotensin-converting enzyme (ACE) 2, a membrane-
bound enzyme of the “alternative”(alt) renin-angiotensin system (RAS). ACE2 counteracts …

Changes in the blood viscosity in patients with SARS-CoV-2 infection

HM Al-Kuraishy, AI Al-Gareeb, SM Al-Hamash… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by a novel virus known as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2-induced …

Quantifying renin-angiotensin-system alterations in COVID-19

F Pucci, F Annoni, RAS Dos Santos, FS Taccone… - Cells, 2021 - mdpi.com
The renin-angiotensin system (RAS) plays a pivotal role in a wide series of physiological
processes, among which inflammation and blood pressure regulation. One of its key …