In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Caco-2, a human intestinal carcinoma cell line, has been used to test the absorption and
transport mechanism of functional foods and drugs across the intestinal epithelium in order …

The kidney plays a critical role in fluid homeostasis, glucose control, and drug excretion.
Loss of kidney function due to drug-induced nephrotoxicity affects over 20% of the adult …

Nonalcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance (IR)
and type 2 diabetes mellitus (T2DM), which are all complex metabolic disorders …

Altered glucose reabsorption via the facilitative glucose transporter 2 (GLUT2) during
diabetes may lead to renal proximal tubule cell (RPTC) injury, inflammation, and interstitial …

Endocannabinoids (eCBs) are internal lipid mediators recognized by the cannabinoid-1 and-
2 receptors (CB 1 R and CB 2 R, respectively), which also mediate the different …

Recent evidence links chronic consumption of large amounts of fructose (FRU) with several
non-communicable disease. After ingestion, dietary FRU is absorbed into the intestinal tract …

Fasting is known to alter the function of various organs and the mechanisms of glucose
metabolism, which affect health outcomes and slow aging. However, it remains unclear how …

Chronic kidney disease (CKD) concerns millions of individuals worldwide, with few
therapeutic strategies available to date. Recent evidence suggests that the …

Avenanthramides are phenolic compounds unique to oats and may contribute to health‐
promoting properties associated with oat consumption. This study used Xenopus laevis …