MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

The discovery that expansion of unstable repeats can cause a variety of neurological
disorders has changed the landscape of disease-oriented research for several forms of …

Stress granules (SGs) are cytoplasmic assemblies of proteins and non-translating mRNAs.
Whereas much has been learned about SG formation, a major gap remains in …

Transcriptomic analyses of postmortem brains have begun to elucidate molecular
abnormalities in autism spectrum disorder (ASD). However, a crucial pathway involved in …

Fragile X syndrome results from the absence of the RNA binding FMR protein. Here, mRNA
was coimmunoprecipitated with the FMRP ribonucleoprotein complex and used to …

Detailed analyses of transcriptome have revealed complexity in regulation of alternative
splicing (AS). These AS events often undergo modulation by genetic variants. Here we …

The Fragile X syndrome, which results from the absence of functional FMRP protein, is the
most common heritable form of mental retardation. Here, we show that FMRP acts as a …

Fragile X syndrome (FXS) is the most common form of inherited mental retardation, and it is
caused by loss of function of the fragile X mental retardation protein (FMRP). FMRP is an …

Spinal muscular atrophy (SMA), one of the most common fatal autosomal recessive
diseases, is characterized by degeneration of motor neurons and muscular atrophy. The …

Fragile X syndrome is caused by a loss of expression of the fragile X mental retardation
protein (FMRP). FMRP is a selective RNA-binding protein which forms a messenger …