Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …

Understanding cancer biology and the development of novel agents for cancer treatment
has always been the goal of cancer researchers. However, the research and development of …

Worldwide, prostate cancer (PC) is the second most frequent cancer among men and the
fifth leading cause of death; moreover, standard treatments for PC have several issues, such …

Prostate cancer (PCa) is the second leading cause of cancer-related death in American
men. PCa that relapses after hormonal therapies, referred to as castration resistant PCa …

Novel treatment targets must be discovered to improve the results for patients with prostate
cancer, which continues to be a significant worldwide health problem. Growth Arrest-Specific …

Azole antifungal drugs have been shown to enhance the cytotoxicity of antimitotic drugs in P-
glycoprotein (P-gp)-overexpressing-resistant cancer cells. Herein, we examined two azole …

Introduction The extensive heterogeneity of prostate cancer (PCa) and multilayered
complexity of progression to castration-resistant prostate cancer (CRPC) have contributed to …

In connection with the emergence of new pathogenic strains of Candida, the search for more
effective antifungal drugs becomes a challenge. Part of the preclinical trials of such drugs …

Ritonavir is a protease inhibitor initially developed for HIV treatment that is now used as a
pharmacokinetic booster for other antiretrovirals due to it being a cytochrome P450 3A4 …

Cynanchum wallichii (CW) is a traditional Chinese medicine which is widely used for
treating arthrophlogosis, traumatic injury, and other conditions. Herein, we investigate the …