Global epidemiology and outcomes of acute kidney injury
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …
aetiologies and pathophysiological processes leading to decreased kidney function. In …
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
An atlas of healthy and injured cell states and niches in the human kidney
Understanding kidney disease relies on defining the complexity of cell types and states, their
associated molecular profiles and interactions within tissue neighbourhoods. Here we …
associated molecular profiles and interactions within tissue neighbourhoods. Here we …
[HTML][HTML] ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury
Y Wang, M Zhang, R Bi, Y Su, F Quan, Y Lin, C Yue… - Redox biology, 2022 - Elsevier
The term ferroptosis coined in 2012 causes acute kidney injury (AKI). However, its pathway
mechanism in AKI is poorly understood. In this study, we conducted an RNA-sequence …
mechanism in AKI is poorly understood. In this study, we conducted an RNA-sequence …
Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury
Drug-induced acute kidney injury (AKI) with a high morbidity and mortality is poorly
diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the …
diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the …
Workers' health and productivity under occupational heat strain: a systematic review and meta-analysis
Background Occupational heat strain (ie, the effect of environmental heat stress on the body)
directly threatens workers' ability to live healthy and productive lives. We estimated the …
directly threatens workers' ability to live healthy and productive lives. We estimated the …
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
Purpose Current reports on acute kidney injury (AKI) in the intensive care unit (ICU) show
wide variation in occurrence rate and are limited by study biases such as use of incomplete …
wide variation in occurrence rate and are limited by study biases such as use of incomplete …
Global morbidity and mortality of leptospirosis: a systematic review
Background Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological
settings and affects vulnerable populations, such as rural subsistence farmers and urban …
settings and affects vulnerable populations, such as rural subsistence farmers and urban …
[HTML][HTML] Acute kidney injury: definition, pathophysiology and clinical phenotypes
K Makris, L Spanou - The clinical biochemist reviews, 2016 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a clinical syndrome that complicates the course and worsens the
outcome in a significant number of hospitalised patients. Recent advances in clinical and …
outcome in a significant number of hospitalised patients. Recent advances in clinical and …
[HTML][HTML] Human urine-derived stem cells protect against renal ischemia/reperfusion injury in a rat model via exosomal miR-146a-5p which targets IRAK1
X Li, J Liao, X Su, W Li, Z Bi, J Wang, Q Su, H Huang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) that
is associated with high morbidity and mortality, and for which specific treatments are lacking …
is associated with high morbidity and mortality, and for which specific treatments are lacking …