Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

HIV biosensors for early diagnosis of infection: The intertwine of nanotechnology with sensing strategies

L Farzin, M Shamsipur, L Samandari, S Sheibani - Talanta, 2020 - Elsevier
Human immunodeficiency virus (HIV) is a lentivirus that leads to acquired immunodeficiency
syndrome (AIDS). With increasing awareness of AIDS emerging as a global public health …

A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples

X Wei, X Wang, Z Zhang, Y Luo, Z Wang… - Nature …, 2022 - nature.com
Despite major advances in HIV testing, ultrasensitive detection of early infection remains
challenging, especially for the viral capsid protein p24, which is an early virological …

Nanopore detection of metal ions: current status and future directions

GM Roozbahani, X Chen, Y Zhang, L Wang… - Small …, 2020 - Wiley Online Library
In this review, recent research efforts that aimed at developing nanopore sensors for
detection of metal ions, which play a crucial role in environmental safety and human health …

Nanopore single-molecule analysis of biomarkers: Providing possible clues to disease diagnosis

X Chen, S Zhou, Y Wang, L Zheng, S Guan… - TrAC Trends in …, 2023 - Elsevier
Biomarker detection has attracted increasing interest in recent years due to the minimally or
non-invasive sampling process. Single entity analysis of biomarkers is expected to provide …

New insights for biosensing: Lessons from microbial defense systems

Y Wan, C Zong, X Li, A Wang, Y Li, T Yang… - Chemical …, 2022 - ACS Publications
Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Molecular recognition and quantification of MLH1, MSH2, MSH6, PMS2, and KRAS in biological samples

RI Stefan-van Staden, RM Ilie-Mihai, M Coros… - ECS Sensors …, 2022 - iopscience.iop.org
Two stochastic sensors based on modification of nitrogen and boron dopped exfoliated
graphene with a complex of protoporphyrin and cobalt, were used for molecular recognition …

Nanobiosensors in diagnostics

A Chamorro-Garcia, A Merkoçi - Nanobiomedicine, 2016 - journals.sagepub.com
Medical diagnosis has been greatly improved thanks to the development of new techniques
capable of performing very sensitive detection and quantifying certain parameters. These …

A Dual‐Response DNA probe for simultaneously monitoring enzymatic activity and environmental pH using a nanopore

L Liu, Y You, K Zhou, B Guo, Z Cao, Y Zhao… - Angewandte …, 2019 - Wiley Online Library
Both protease overexpression and local pH changes are key signatures of cancer. However,
the sensitive detection of protease activities and the accurate measurement of pH in a tumor …

Proteomic and post‐translational modification profiling of exosome‐mimetic nanovesicles compared to exosomes

A Nasiri Kenari, K Kastaniegaard, DW Greening… - …, 2019 - Wiley Online Library
Issues associated with upscaling exosome production for therapeutic use may be overcome
through utilizing artificial exosomes. Cell‐derived mimetic nanovesicles (M‐NVs) are a …