Steroidal resource occupies a vital proportion in the pharmaceutical industry attributing to
their important therapeutic effects on fertility, anti-inflammatory and antiviral activities …

Tuberculosis (TB), induced by Mycobacterium tuberculosis (MTB), is a fatal infectious
disease that kills millions of lives worldwide. The emergence of drug-resistant and multidrug …

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commercial purposes, provided the work is appropriately cited, as indicated below. In any …

Metabolic flux is the final output of cellular regulation and has been extensively studied for
carbon but much less is known about nitrogen, which is another important building block for …

Described here is a series of spiropyrimidinetrione (SPT) compounds with activity against
Mycobacterium tuberculosis through inhibition of DNA gyrase. The SPT class operates via a …

Mycobacterium tuberculosis (Mtb) has an impermeable cell wall which gives it an inherent
ability to resist many antibiotics. DprE1, an essential enzyme in Mtb cell wall synthesis, has …

Understanding the complex mechanisms of mycobacterial pathophysiology and adaptive
responses presents challenges that can hinder drug development. However, employing …

Context: Eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid are the
significant members of the ω-3 fatty acid group. Their beneficial pharmacological effects …

Curcumin is a natural product that has been reported to exhibit myriad pharmacological
properties, one of which is antitubercular activity. It demonstrates antitubercular activity by …

The use of detergents when culturing Mycobacterium tuberculosis (M. tuberculosis) are
essential to prevent clumping. However, these detergents may influence research outcomes …