Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

There is significant interest in understanding inflammatory responses within the brain and
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …

Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

A single traumatic brain injury is associated with an increased risk of dementia and, in a
proportion of patients surviving a year or more from injury, the development of hallmark …

Glia of the central nervous system (CNS) help to maintain homeostasis in the brain and
support efficient neuronal function. Microglia are innate immune cells of the brain that …

Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …

Traumatic brain injury (TBI) affects millions of people worldwide every year. The primary
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …

Neuronal and glial cell death and traumatic axonal injury contribute to the overall pathology
of traumatic brain injury (TBI) in both humans and animals. In both head‐injured humans …

Background Traumatic brain injury (TBI) is associated with a higher incidence of depression.
The majority of individuals who suffer a TBI are juveniles and young adults, and thus, the risk …

Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …