The gut microbiota represents a 'metabolic organ'that can regulate human metabolism. Intact
gut microbiota contributes to host homeostasis, whereas compositional perturbations …

Intestinal microbiota are involved in the pathogenesis of Crohn's disease, ulcerative colitis,
and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses …

The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …

In order for human microbiome studies to translate into actionable outcomes for health, meta-
analysis of reproducible data from population-scale cohorts is needed. Achieving sufficient …

An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract. Although the etiology and pathogenesis of IBD remain unclear, both genetic …

Background Chemotherapy is commonly used as myeloablative conditioning treatment to
prepare patients for haematopoietic stem cell transplantation (HSCT). Chemotherapy leads …

Shotgun metagenomics and computational analysis are used to compare the taxonomic and
functional profiles of microbial communities. Leveraging this approach to understand roles of …

Ticks are obligate blood-feeders and serve as vectors of human and livestock pathogens
worldwide. Defining the tick microbiome and deciphering the interactions between the tick …

Growing interest in microbial contributions to human health and disease has increasingly
led investigators to examine the microbiome in both healthy skin and cutaneous disorders …