Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

The trans-Golgi network (TGN) is an important cargo sorting station within the cell where
newly synthesized proteins are packaged into distinct transport carriers that are targeted to …

Protein S‐palmitoylation (hereinafter referred to as protein palmitoylation) is a reversible
lipid posttranslational modification catalyzed by the zinc finger DHHC‐type containing …

The Atg8 autophagy proteins are essential for autophagosome biogenesis and maturation.
The γ-aminobutyric acid receptor-associated protein (GABARAP) Atg8 family is much less …

To maintain an asymmetric distribution of ions across membranes, protein pumps displace
ions against their concentration gradient by using chemical energy. Here, we describe a …

Lipids must be correctly transported within the cell to the right place at the right time in order
to be fully functional. Non-vesicular lipid transport is mediated by so-called lipid transfer …

Abstract Phosphatidylinositol 4-phosphate (PI4P) is a membrane glycerophospholipid and a
major regulator of the characteristic appearance of the Golgi complex as well as its vesicular …

Several RNA viruses have recently been shown to hijack members of the host
phosphatidylinositol (PtdIns) 4-kinase (PI4K) family of enzymes. They use PI4K to generate …