Sperm DNA methylation patterns at discrete CpGs and genes involved in embryonic development are related to bull fertility

M Štiavnická, A Chaulot-Talmon, JP Perrier, P Hošek… - BMC genomics, 2022 - Springer
Background Despite a multifactorial approach being taken for the evaluation of bull semen
quality in many animal breeding centres worldwide, reliable prediction of bull fertility is still a …

Variable Cre Recombination Efficiency in Placentas of Cyp19-Cre ROSAmT/mG Transgenic Mice

P Anamthathmakula, PD Shallie, N Nayak, S Dhal… - Cells, 2023 - mdpi.com
The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been
extensively used for placenta-specific gene inactivation. In a pilot study, we observed …

Loss of DNA methylation disrupts syncytiotrophoblast development: Proposed consequences of aberrant germline gene activation

G Lea, CW Hanna - BioEssays, 2024 - Wiley Online Library
DNA methylation is a repressive epigenetic modification that is essential for development
and its disruption is widely implicated in disease. Yet, remarkably, ablation of DNA …

Wnt4, Wnt6 and β-catenin expression in human placental tissue–is there a link with first trimester miscarriage? Results from a pilot study

E Chronopoulou, V Koika, K Tsiveriotis… - Reproductive Biology …, 2022 - Springer
Background Demystifying the events around early pregnancy is challenging. A wide network
of mediators and signaling cascades orchestrate the processes of implantation and …

[HTML][HTML] Basic Research Advances in China on Embryo Implantation, Placentation, and Parturition

H Bao, H Wang - Maternal-Fetal Medicine, 2024 - journals.lww.com
This review aimed to summarize the major progress in maternal-fetal medicine achieved by
Chinese scientists in recent years. PubMed was systematically searched from January 2020 …

ASCL2 is a key regulator of the proliferation–differentiation equilibrium in the esophageal epithelium

M Hamilton, Z Mars, M Sedeuil, M Rolland… - Biology …, 2024 - journals.biologists.com
The esophagus is protected from the hostile environment by a stratified epithelium, which
renews rapidly. Homeostasis of this epithelium is ensured by a rare population of stem cells …

Elevated serum SFRP5 levels during preeclampsia and its potential association with trophoblast dysfunction via Wnt/β-catenin suppression

Y Zhang, Y Ran, Y Ma, H Huang, Y Chen, H Qi - Reproductive Sciences, 2022 - Springer
Preeclampsia (PE) is a life-threatening pregnancy complication associated with diminished
trophoblast migration and invasion. Wnt signalling is one of the most important regulators of …

Combination of 308‐nm excimer laser and piperine promotes melanocyte proliferation, migration, and melanin content production via the miR‐328/SFRP1 axis

Y Wu, J Zhang, S Du, X Wang, J Li… - Photodermatology …, 2024 - Wiley Online Library
Objective Both piperine and a 308‐nm excimer laser have significant curative effects on
vitiligo. This study mainly explored the molecular mechanism of a 308‐nm excimer …

Alternative Splicing Landscape of Placental Decidual Cells during Physiological Pregnancy

EA Trifonova, MM Gavrilenko, AA Babovskaya… - Russian Journal of …, 2022 - Springer
Alternative splicing (AS) of RNA is a key step in the post-transcriptional regulation of gene
expression. It provides transcriptional plasticity and control of the expression of RNA …

Maternal exposure to tributyltin during early gestation increases adverse pregnancy outcomes by impairing placental development

H Liu, W Jiang, Y Ye, B Yang, X Shen… - Environmental …, 2021 - Wiley Online Library
Tributyltin (TBT) is a persistent organotin pollutant widely used as agricultural and wood
biocides, exhibiting well‐documented toxicity to reproductive functions in aquatic organisms …