Medicinal chemistry meets proteomics: fractionation of the human plasma proteome
Human plasma and its fractions/derivatives are frequently used materials in biomedicine as
it contains thousands and thousands of proteins representing the majority of human …
it contains thousands and thousands of proteins representing the majority of human …
Molecular engineering of cyclic azobenzene‐peptide hybrid ligands for the purification of human blood factor VIII via photo‐affinity chromatography
The use of benign stimuli to control the binding and release of labile biologics for their
isolation from complex feedstocks is a key goal of modern biopharmaceutical technology …
isolation from complex feedstocks is a key goal of modern biopharmaceutical technology …
Photodegradation pathways of protein disulfides: human growth hormone
D Steinmann, O Mozziconacci, R Bommana… - Pharmaceutical …, 2017 - Springer
Purpose Comprehensive product characterization was performed for the photodegradation
of protein disulfides, representatively of human growth hormone (somatotropin; hGH), in …
of protein disulfides, representatively of human growth hormone (somatotropin; hGH), in …
Intensified capture of recombinant blood coagulation factors by continuous, integrated downstream processing
H Engelmaier, C Dattenböck… - Journal of Chemical …, 2024 - Wiley Online Library
BACKGROUND The biopharmaceutical community has realized the tremendous potential of
continuous processing for process intensification. However, to date reports of continuous …
continuous processing for process intensification. However, to date reports of continuous …
超大孔离子交换制备色谱分离纯化高活性凝血因子VIII
康丽梅， 张焱， 罗坚， 李由， 周月芳， 余蓉， 苏志国 - 色谱, 2012 - chrom-china.com
建立了一条从人血浆中分离高活性凝血因子VIII (FVIII) 的纯化工艺. 基于FVIII
和介质孔径的尺度比及其对蛋白质活性影响的分析, 设计了以超大孔离子交换制备色谱为核心 …
和介质孔径的尺度比及其对蛋白质活性影响的分析, 设计了以超大孔离子交换制备色谱为核心 …
Non-cryoprecipitation separation of coagulation FVIII and prothrombin complex proteins by pseudoaffinity calcium elution chromatography using anion exchange resin
GP Feliciano, SH Arimori, VW Nakao, JR Dos Santos… - Pharmaceuticals, 2022 - mdpi.com
Hemophilia A is treated with human plasma coagulation factor VIII (FVIII) replacement
therapy and Hemophilia B with coagulation factor IX, which is purified from prothrombin …
therapy and Hemophilia B with coagulation factor IX, which is purified from prothrombin …
[HTML][HTML] Depletion of plasma albumin for proteomic analysis of Bothrops jararaca snake plasma
The proteomic analysis of plasma samples represents a challenge as a result of the
presence of highly abundant proteins such as albumin. To enable the detection of …
presence of highly abundant proteins such as albumin. To enable the detection of …
Purification of coagulation factor VIII by immobilized metal affinity chromatography
ES Rodrigues, CI Verinaud, DS Oliveira… - Biotechnology and …, 2015 - Wiley Online Library
Factor VIII (FVIII) is a glycoprotein that plays an essential role in blood coagulation cascade.
Purification of plasma‐derived coagulation FVIII by direct application of plasma to a …
Purification of plasma‐derived coagulation FVIII by direct application of plasma to a …
[HTML][HTML] Challenges to design and develop of DNA aptamers for protein targets. II. Development of the aptameric affinity ligands specific to human plasma coagulation …
H Vahidi, N Nafissi-Varcheh, B Kazemi… - Iranian Journal of …, 2017 - ncbi.nlm.nih.gov
Protein specific aptamers are highly applicable affinity ligands in different fields of research
and clinical applications. They have been developed against various targets, in particular …
and clinical applications. They have been developed against various targets, in particular …