Site‐specific glycosylation of SARS‐CoV‐2: Big challenges in mass spectrometry analysis
D Campos, M Girgis, M Sanda - Proteomics, 2022 - Wiley Online Library
Glycosylation of viral proteins is required for the progeny formation and infectivity of virtually
all viruses. It is increasingly clear that distinct glycans also play pivotal roles in the virus's …
all viruses. It is increasingly clear that distinct glycans also play pivotal roles in the virus's …
Structure and Role of O-Linked Glycans in Viral Envelope Proteins
S Olofsson, M Bally, E Trybala… - Annual review of …, 2023 - annualreviews.org
N-and O-glycans are both important constituents of viral envelope glycoproteins. O-linked
glycosylation can be initiated by any of 20 different human polypeptide O …
glycosylation can be initiated by any of 20 different human polypeptide O …
Analysis of the N-glycosylation profiles of the spike proteins from the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2
N-Glycosylation plays an important role in the structure and function of membrane and
secreted proteins. Viral proteins used in cell entry are often extensively glycosylated to assist …
secreted proteins. Viral proteins used in cell entry are often extensively glycosylated to assist …
Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron
M Benlarbi, G Laroche, C Fink, K Fu, RP Mulloy… - IScience, 2022 - cell.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S)
binds to angiotensin-converting enzyme 2 (ACE2) to mediate membrane fusion via two …
binds to angiotensin-converting enzyme 2 (ACE2) to mediate membrane fusion via two …
Analysis of viral spike protein N-glycosylation using ultraviolet photodissociation mass spectrometry
EE Escobar, S Wang, R Goswami… - Analytical …, 2022 - ACS Publications
Characterization of protein glycosylation by tandem mass spectrometry remains challenging
owing to the vast diversity of oligosaccharides bound to proteins, the variation in …
owing to the vast diversity of oligosaccharides bound to proteins, the variation in …
Determining site-specific glycan profiles of recombinant SARS-CoV-2 spike proteins from multiple sources
MC Burke, Y Liu, C Remoroza… - Journal of Proteome …, 2023 - ACS Publications
Glycopeptide Abundance Distribution Spectra (GADS) were recently introduced as a means
of representing, storing, and comparing glycan profiles of intact glycopeptides. Here, using …
of representing, storing, and comparing glycan profiles of intact glycopeptides. Here, using …
[HTML][HTML] Evolving spike-protein N-glycosylation in SARS-CoV-2 variants
Abstract Since> 3 years, SARS-CoV-2 has plunged humans into a colossal pandemic.
Henceforth, multiple waves of infection have swept through the human population, led by …
Henceforth, multiple waves of infection have swept through the human population, led by …
SP-A binding to the SARS-CoV-2 spike protein using hybrid quantum and classical in silico modeling and molecular pruning by Quantum Approximate Optimization …
S Aramyan, K McGregor, S Sandeep… - Frontiers in …, 2022 - frontiersin.org
The pulmonary surfactant protein A (SP-A) is a constitutively expressed immune-protective
collagenous lectin (collectin) in the lung. It binds to the cell membrane of immune cells and …
collagenous lectin (collectin) in the lung. It binds to the cell membrane of immune cells and …
SARS-CoV-2 activates ER stress and Unfolded protein response
ABSTRACT Coronavirus disease-2019 (COVID-19) pandemic caused by the SARS-CoV-2
coronavirus infection is a major global public health concern affecting millions of people …
coronavirus infection is a major global public health concern affecting millions of people …
Suppression of O-linked glycosylation of the SARS-CoV-2 spike by quaternary structural restraints
Understanding the glycosylation of the envelope spike (S) protein of SARS-CoV-2 is
important in defining the antigenic surface of this key viral target. However, the underlying …
important in defining the antigenic surface of this key viral target. However, the underlying …