[HTML][HTML] Cell death due to electroporation–a review

TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

[HTML][HTML] Effects of high voltage nanosecond electric pulses on eukaryotic cells (in vitro): A systematic review

TB Napotnik, M Reberšek, PT Vernier, B Mali… - …, 2016 - Elsevier
For this systematic review, 203 published reports on effects of electroporation using
nanosecond high-voltage electric pulses (nsEP) on eukaryotic cells (human, animal, plant) …

Ultrashort electrical pulses open a new gateway into biological cells

KH Schoenbach, RP Joshi, JF Kolb… - Proceedings of the …, 2004 - ieeexplore.ieee.org
An electrical model for biological cells predicts that for pulses with durations shorter than the
charging time of the outer membrane, there is an increasing probability of electric field …

Calcium bursts induced by nanosecond electric pulses

PT Vernier, Y Sun, L Marcu, S Salemi, CM Craft… - Biochemical and …, 2003 - Elsevier
We report here real-time imaging of calcium bursts in human lymphocytes exposed to
nanosecond, megavolt-per-meter pulsed electric fields. Ultra-short (less than 30ns), high …

Bioelectric effects of intense nanosecond pulses

KH Schoenbach, SJ Hargrave, RP Joshi… - … on Dielectrics and …, 2007 - ieeexplore.ieee.org
Electrical models for biological cells predict that reducing the duration of applied electrical
pulses to values below the charging time of the outer cell membrane (which is on the order …

Nanoelectropulse-driven membrane perturbation and small molecule permeabilization

PT Vernier, Y Sun, MA Gundersen - BMC cell biology, 2006 - Springer
Background Nanosecond, megavolt-per-meter pulsed electric fields scramble membrane
phospholipids, release intracellular calcium, and induce apoptosis. Flow cytometric and …

Induction of cell death mechanisms and apoptosis by nanosecond pulsed electric fields (nsPEFs)

SJ Beebe, NM Sain, W Ren - Cells, 2013 - mdpi.com
Pulse power technology using nanosecond pulsed electric fields (nsPEFs) offers a new
stimulus to modulate cell functions or induce cell death for cancer cell ablation. New data …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

[HTML][HTML] Nanoelectropulse-induced phosphatidylserine translocation

PT Vernier, Y Sun, L Marcu, CM Craft, MA Gundersen - Biophysical journal, 2004 - cell.com
Abstract Nanosecond, megavolt-per-meter, pulsed electric fields induce phosphatidylserine
(PS) externalization, intracellular calcium redistribution, and apoptosis in Jurkat T …

Starting a fire without flame: The induction of cell death and inflammation in electroporation-based tumor ablation strategies

RM Brock, N Beitel-White, RV Davalos, IC Allen - frontiers in oncology, 2020 - frontiersin.org
New therapeutic strategies and paradigms are direly needed for the treatment of cancer.
While the surgical removal of tumors is favored in most cancer treatment plans, resection …