Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

ABSTRACT The genus Streptococcus includes Gram-positive organisms shaped in cocci
and organized in chains. They are commensals, pathogens, and opportunistic pathogens for …

Gasdermins, a family of five pore-forming proteins (GSDMA–GSDME) in humans expressed
predominantly in the skin, mucosa and immune sentinel cells, are key executioners of …

Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a Gram-positive
human-exclusive pathogen, responsible for more than 500 000 deaths annually worldwide …

Lower respiratory tract infections and tuberculosis are responsible for the death of about 4.5
million people each year and are the main causes of mortality in children under 5 years of …

Ammonia is a known environmental pollutant that causes injury to the intestine. Growing
evidence suggests that intestinal microbiota dysbiosis involves in the development of …

Peptide-based vaccines have the potential to overcome the limitations of classical vaccines;
however, their use is hampered by a lack of carriers and adjuvants suitable for human use …

The human complement system plays an important role in the defense against invading
pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly …

Gram-positive bacteria colonize mucosal tissues, withstanding large mechanical
perturbations such as coughing, which generate shear forces that exceed the ability of non …

Mercury is a key global pollutant, yet the mechanism by which mercury-exposure causes
intestinal injury is not clear, we aimed to investigate the mechanism of intestinal injury and …