Pyroptosis: a new regulating mechanism in cardiovascular disease

N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - Journal of …, 2021 - Taylor & Francis
Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and
apoptosis, pyroptosis has unique characteristics in morphology and mechanism …

[HTML][HTML] Macrophage subsets and death are responsible for atherosclerotic plaque formation

H Li, Z Cao, L Wang, C Liu, H Lin, Y Tang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …

Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell

A Takahashi, A Yousif, L Hong, II Chefetz - Journal of Molecular Medicine, 2021 - Springer
Primary ovarian insufficiency (POI) is defined as a reduction in ovarian function before the
expected age of menopause. POI is known to increase the risk of cardiovascular disorders …

Natural products targeting signaling pathways associated with regulated cell death in gastric cancer: Recent advances and perspectives

Q Hu, Z Li, Y Li, X Deng, Y Chen, X Ma… - Phytotherapy …, 2023 - Wiley Online Library
Gastric cancer (GC) is one of the most serious gastrointestinal malignancies with high
morbidity and mortality. The complexity of GC process lies in the multi‐phenotypic linkage …

[HTML][HTML] The development of necroptosis: what we can learn

D Ma, X Wang, J Liu, Y Cui, S Luo, F Wang - Cell Stress and Chaperones, 2023 - Elsevier
Necroptosis is a new type of programmed cell death discovered in recent years, playing an
important role in various diseases. Since it was conceptualized in 2005, research on …

[HTML][HTML] The impact of aging on macroautophagy in the pre-ovulatory mouse oocyte

AE Peters, SJ Caban, EA McLaughlin… - Frontiers in Cell and …, 2021 - frontiersin.org
Accompanying the precipitous age-related decline in human female fertility is an increase in
the proportion of poor-quality oocytes within the ovary. The macroautophagy pathway, an …

Therapeutic effect of melatonin in premature ovarian insufficiency: hippo pathway is involved

MK Qi, TC Sun, LY Yang, JL He, YM Guo… - Oxidative medicine …, 2022 - Wiley Online Library
Objective. Premature ovarian insufficiency (POI) is a female reproductive disorder of
unknown etiology with no definite pathogenesis. Melatonin (MT) is an endogenous hormone …

[HTML][HTML] The activation of reticulophagy by ER stress through the ATF4-MAP1LC3A-CCPG1 pathway in ovarian granulosa cells is linked to apoptosis and necroptosis

H Li, Y Jing, X Qu, J Yang, P Pan, X Liu, H Gao… - International Journal of …, 2023 - mdpi.com
Female infertility is caused by premature ovarian failure (POF), which is triggered by the
endoplasmic reticulum (ER) stress-mediated apoptosis of granulosa cells. The ER unfolded …

Recombinant human growth hormone treatment of mice suppresses inflammation and apoptosis caused by skin flap ischemia–reperfusion injury

B Liu, Q Xu, J Wang, J Lin, Y Pei, Y Cui… - Journal of cellular …, 2019 - Wiley Online Library
Background This study was to investigate the effects of recombinant human growth hormone
(rhGh) on ischemia‐reperfusion (I/R) injury of mouse flaps. Methods Healthy mice were …

[HTML][HTML] Unraveling the puzzle: Oocyte maturation abnormalities (OMAS)

S Hatirnaz, E Hatirnaz, S Çelik, CS Çalışkan, A Tinelli… - Diagnostics, 2022 - mdpi.com
Oocyte maturation abnormalities (OMAS) are a poorly understood area of reproductive
medicine. Much remains to be understood about how OMAS occur. However, current …