[HTML][HTML] MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside

M Ratti, A Lampis, M Ghidini, M Salati, MB Mirchev… - Targeted …, 2020 - Springer
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

[HTML][HTML] Galectin-3 in cardiovascular diseases

V Blanda, UM Bracale, MD Di Taranto… - International journal of …, 2020 - mdpi.com
Galectin-3 (Gal-3) is a β-galactoside-binding protein belonging to the lectin family with
pleiotropic regulatory activities and several physiological cellular functions, such as cellular …

[HTML][HTML] Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics

H Chen, C Chen, M Spanos, G Li, R Lu, Y Bei… - … and Targeted Therapy, 2022 - nature.com
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …

Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4

H Li, JD Xu, XH Fang, JN Zhu, J Yang… - Cardiovascular …, 2020 - academic.oup.com
Abstract Aims Circular RNAs (circRNAs) are involved in gene regulation in a variety of
physiological and pathological processes. The present study aimed to investigate the effect …

The role of long noncoding RNA in major human disease

X Zhang, R Hong, W Chen, M Xu, L Wang - Bioorganic chemistry, 2019 - Elsevier
Abstract Background Long noncoding RNAs (lncRNAs) are RNAs whose transcripts are
longer than 200nt in length and lack the ability to encode proteins due to lack of specific …

Circulating lncRNA SNHG11 as a novel biomarker for early diagnosis and prognosis of colorectal cancer

W Xu, G Zhou, H Wang, Y Liu, B Chen… - … journal of cancer, 2020 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer mortality worldwide. Emerging evidence indicates that tumour cells release …

[HTML][HTML] Heart failure with preserved ejection fraction: a review of cardiac and noncardiac pathophysiology

AB Gevaert, JRA Boen, VF Segers… - Frontiers in …, 2019 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is one of the largest unmet clinical
needs in 21st-century cardiology. It is a complex disorder resulting from the influence of …

[HTML][HTML] Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges

J Meyer, S Naiken, N Christou, E Liot… - World journal of …, 2019 - ncbi.nlm.nih.gov
Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b

SF Sun, PMK Tang, M Feng, J Xiao, XR Huang, P Li… - Diabetes, 2018 - Am Diabetes Assoc
Transforming growth factor-β/Smad signaling plays an important role in diabetic
nephropathy. The current study identified a novel Smad3-dependent long noncoding RNA …

Comparative analysis of circulating noncoding RNAs versus protein biomarkers in the detection of myocardial injury

C Schulte, T Barwari, A Joshi, K Theofilatos… - Circulation …, 2019 - Am Heart Assoc
Rationale: Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), circular RNAs
(circRNAs), and long noncoding RNAs (lncRNAs), are proposed novel biomarkers of …