Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Over the past decade, traditional Chinese medicine (TCM) has widely embraced systems
biology and its various data integration approaches to promote its modernization. Thus …

Abstract Purpose of the Review The purpose of this review is to summarize and evaluate
relevant literature on combination antifungal therapy for invasive fungal infections (IFIs) …

Invasive aspergillosis (IA) is associated with significant morbidity and mortality. Voriconazole
remains the drug of choice for the treatment of IA in children; however, the complex kinetics …

Cytochrome P450 (P450) enzymes metabolize arachidonic acid (AA) to several biologically
active epoxyeicosatrienoic acids (EETs) and hydroxyeicosatetraenoic acids (HETEs) …

Introduction Severe fever with thrombocytopenia syndrome (SFTS) has been prevalent in
parts of Asia during recent years. However, SFTS with invasive pulmonary aspergillosis …

In this study, the in vitro interactions of amphotericin B (AmB), voriconazole (VRC) and
anidulafungin (AFG) in double and triple combinations against four species of multiresistant …

Background Combination therapy of voriconazole with an echinocandin is often employed in
order to increase the efficacy of voriconazole monotherapy. Methods Four clinical …

Scedosporium and Fusarium species are emerging opportunistic pathogens, causing
invasive fungal diseases in humans, particularly in immunocompromised patients. Biofilm …

This book is designed to provide a comprehensive but insightful examination of antifungal
therapy in the changing clinical milieu of modern medicine. It is an update from the original …