Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Motor deficits usually associated with PD correlate with dopaminergic axonal …

Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Parkinson's disease (PD) is the second most common neurodegenerative disease. About
2% of the population above the age of 60 is affected by the disease. The pathological …

Ferroptosis, a novel form of regulated cell death, is caused by accumulation of lipid
peroxides and excessive iron deposition. This process has been linked to the death of …

Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

Autophagy and apoptosis are basic physiologic processes contributing to the maintenance
of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …

The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …

Parkinson disease (PD) is the second most common neurodegenerative disorder after
Alzheimer disease and is caused by genetics, environmental factors and aging, with few …