Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

The WNT/β-catenin signaling pathway is a highly conserved and tightly controlled molecular
mechanism that regulates embryonic development, cellular proliferation and differentiation …

Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are
highly specialized cells residing in a complex anatomic niche where they participate in bile …

The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …

Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …

Cholangiocarcinoma (CCA) is a malignant tumour arising from the biliary system. In Europe,
this tumour frequently presents as a sporadic cancer in patients without defined risk factors …

Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In
advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective …

The high mortality rate of cholangiocarcinoma (CCA) is due, in part, to the lack of non‐
invasive approaches able to accurately detect this silent tumour at early stages, when …

Cholangiocarcinoma (CCA) is a rare malignancy that develops at any point along the biliary
tree. CCA has a poor prognosis, its clinical management remains challenging, and effective …