Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression
Major depressive disorder is a highly debilitating psychiatric disorder involving the
dysfunction of different cell types in the brain. Microglia are the predominant resident …
dysfunction of different cell types in the brain. Microglia are the predominant resident …
NLRP3 inflammasome-driven pathways in depression: clinical and preclinical findings
Over the past three decades, an intricate interaction between immune activation, release of
pro-inflammatory cytokines and changes in brain circuits related to mood and behavior has …
pro-inflammatory cytokines and changes in brain circuits related to mood and behavior has …
Chemokine dysregulation and neuroinflammation in schizophrenia: a systematic review
EA Ermakov, IA Mednova, AS Boiko… - International Journal of …, 2023 - mdpi.com
Chemokines are known to be immunoregulatory proteins involved not only in lymphocyte
chemotaxis to the site of inflammation, but also in neuromodulation, neurogenesis, and …
chemotaxis to the site of inflammation, but also in neuromodulation, neurogenesis, and …
Intergenerational transmission of depression: clinical observations and molecular mechanisms
KM Sawyer, PA Zunszain, P Dazzan… - Molecular psychiatry, 2019 - nature.com
Maternal mental illness can have a devastating effect during the perinatal period, and has a
profound impact on the care that the baby receives and on the relationships that the baby …
profound impact on the care that the baby receives and on the relationships that the baby …
The potential role of dysfunctions in neuron-microglia communication in the pathogenesis of brain disorders
K Chamera, E Trojan… - Current …, 2020 - ingentaconnect.com
The bidirectional communication between neurons and microglia is fundamental for the
proper functioning of the central nervous system (CNS). Chemokines and clusters of …
proper functioning of the central nervous system (CNS). Chemokines and clusters of …
[HTML][HTML] Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats
Prenatal alcohol exposure (PAE) can result in neurobehavioral anomalies, that may be
exacerbated by co-occurring metabolic and immune system deficits. To test the hypothesis …
exacerbated by co-occurring metabolic and immune system deficits. To test the hypothesis …
The prenatal challenge with lipopolysaccharide and polyinosinic: polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat …
K Chamera, K Kotarska, M Szuster-Głuszczak… - Journal of …, 2020 - Springer
Background The bidirectional communication between neurons and microglia is
fundamental for the homeostasis and biological function of the central nervous system …
fundamental for the homeostasis and biological function of the central nervous system …
Regulation of CNS precursor function by neuronal chemokines
AES Watson, K Goodkey, T Footz, A Voronova - Neuroscience letters, 2020 - Elsevier
Oligodendrocyte and neural precursor cells (OPCs and NPCs, respectively) in the central
nervous system (CNS) have diverse roles in development and homeostasis. During …
nervous system (CNS) have diverse roles in development and homeostasis. During …
Targeting the NLRP3 inflammasome in neuroinflammation: health promoting effects of dietary phytochemicals in neurological disorders
WL Hung, CT Ho, MH Pan - Molecular nutrition & food research, 2020 - Wiley Online Library
Neurological disorders occur in the central and peripheral nervous system and include
Alzheimer's disease, stroke, and spinal cord injury. Activation of the innate immune system …
Alzheimer's disease, stroke, and spinal cord injury. Activation of the innate immune system …
Melatonin reverses the depression-associated behaviour and regulates microglia, fractalkine expression and neurogenesis in adult mice exposed to chronic mild …
NM Vega-Rivera, L Ortiz-López, A Granados-Juárez… - Neuroscience, 2020 - Elsevier
Depression may be precipitated by the negative impact of chronic stress, which is
considered to play a key role in this neuropsychiatric disorder. Interestingly, depressed …
considered to play a key role in this neuropsychiatric disorder. Interestingly, depressed …