New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

B. pseudomallei is the cause of melioidosis, a serious an often fatal disease of humans and
animals. The closely related bacterium B. mallei, which cases glanders, is considered to be …

Supercoiled flagellar filaments function as mechanical propellers within the bacterial
flagellum complex, playing a crucial role in motility. Flagellin, the building block of the …

SARS-CoV-2 is a health threat with dire socioeconomical consequences. As the crucial
mediator of infection, the viral glycosylated spike protein (S) has attracted the most attention …

Many bacteria require flagella for the ability to move, survive, and cause infection. The
flagellum is a complex nanomachine that has evolved to increase the fitness of each …

The SARS-CoV-2 spike (S) protein is exposed on the viral surface and is the first point of
contact between the virus and the host. For these reasons it represents the prime target for …

The bacterial flagellum is a motile organelle composed of thousands of protein subunits. The
filamentous part that extends from the cell membrane is called the axial structure and …

FliD is a self-oligomerizing structural protein that caps the growing end of the bacterial
flagellar filament. FliD also plays a key role in the flagellar system by continuously adding a …

Zinc deficiency impairs the antibody-mediated immune response and is common in children
from lower-income countries. This study aimed to investigate the impact of different zinc …

Successful bacterial pathogens have evolved to avoid activating an innate immune system
in the host that responds to the pathogen through distinct Toll-like receptors (TLRs). The …