Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …

(R)-Ricinoleic acid (RA)[(12R, 9Z)-hydroxyoctadecenoic acid], the main compound of castor
seed oil, because of its unusual structure readily undergoes multi-directional chemical and …

Carvacrol has been described as an agonist/antagonist of different transient receptor
potential (TRP) channels and voltage-dependent calcium channels (Ca vs). The aim of this …

This paper is a review on the types of antagonists and the signaling mechanism pathways
that have been used to determine the mechanisms of action employed for vasodilation by …

Moderate consumption of wine has a protective effect on the cardiovascular system. This
study proposes to investigate the cardiovascular protective effect of the lyophilized red wine …

Organic nitrates are widely used to restore endogenous nitric oxide (NO) levels reduced by
endothelial nitric oxide synthase dysfunction. However, these drugs are associated with …

Pharmacokinetic Properties using Graph-Based Signatures). Os parâmetros físicoquímicos
e a predição ADMET sugeriram que o NDIBP apresentou boa biodisponibilidade oral …

As doenças cardiovasculares são a principal causa de mortes no mundo, matando cerca de
17 milhões de pessoas por ano, segundo a Organização Mundial de Saúde. Um dos …

PARTICIPAÇÃO DOS CANAIS TRP NO EFEITO VASORRELAXANTE DE R(+)-PULEGONA EM
RATOS NORMOTENSOS Page 1 UNIVERSIDADE FEDERAL DE SERGIPE PRÓ-REITORIA DE …

Hipertensão e diabetes são patologias com forte impacto na saúde pública e possuem
como fatores de risco, hábitos alimentares incorretos e estresse oxidativo. Neste sentido, a …