Lipoprotein lipase (LPL) is a rate-limiting enzyme for hydrolysing circulating triglycerides
(TG) into free fatty acids that are taken up by peripheral tissues. Postprandial LPL activity …

Long-term controversy regarding the role of angiopoietin-like protein 8 (ANGPTL8) in beta-
cell proliferation and diabetes progression made it a research spotlight. Recently, the …

ANGPTL8 is an important cytokine, which is significantly increased in type 2 diabetes
mellitus (T2DM), obesity and metabolic syndrome. Many studies have shown that ANGPTL8 …

Diabetic nephropathy (DN) is a complicated condition related to type 2 diabetes mellitus
(T2D). ANGPTL8 is a hepatic protein highlighted as a risk factor for DN in patients with T2D; …

Context: Angiopoietin-like protein 8 (ANGPTL8)/betatrophin is a secreted protein initially
involved in β-cell replication. Recent data in humans and mice models suggest that …

Background. Psoriasis is a chronic systemic inflammatory disease associated with a wide
range of comorbidities, including metabolic syndrome (MetS). Serum calprotectin …

Angiopoietin-like protein 8 (ANGPTL8) is a secreted protein predominantly expressed in
liver and adipose tissue. ANGPTL8 modulates the clearance of triglycerides (TGs) by …

Betatrophin (angiopoietin-like protein 8 (ANGPTL8)) is a hormone that was recently
discovered in the human liver. Multiple homologous sequences have been detected in …

Background Betatrophin has been recently reported to play a role in glucose homeostasis
by inducing beta-cell proliferation in mice. However, studies in human are inconsistent. As a …

Background Hypertriglyceridemia, insulin resistance and hyperglycemia are risk factors for
atherosclerosis in type 2 diabetes. Angiopoietin-like protein 8 (ANGPTL8) is a newly …