D1R-5-HT2AR Uncoupling Reduces Depressive Behaviours via HDAC Signalling

W Li, T Ali, S Mou, Q Gong, N Li, L Hao, ZJ Yu, S Li - Neurotherapeutics, 2023 - Springer
Dopamine and serotonin signalling are associated with major depressive disorder, which is
a prevalent life-threatening illness worldwide. Numerous FDA-approved …

Preclinical Evidence for the Role of the Yin/Yang Angiotensin System Components in Autism Spectrum Disorder: A Therapeutic Target of Astaxanthin

AI Samra, AS Kamel, DM Abdallah, MAA El Fattah… - Biomedicines, 2023 - mdpi.com
Autism spectrum disorder (ASD) prevalence is emerging with an unclear etiology, hindering
effective therapeutic interventions. Recent studies suggest potential renin–angiotensin …

Captopril prevents depressive-like behavior in an animal model of depression by enhancing hippocampal neurogenesis via activation of the ACE2/Ang (1–7)/Mas …

T Odaira-Satoh, O Nakagawasai, K Takahashi… - Progress in Neuro …, 2025 - Elsevier
Abstract The brain's Renin-Angiotensin System plays an important role in the modulation of
mental state. Previously we demonstrated that activated angiotensin (Ang) converting …

[HTML][HTML] Aliskiren

TF Jacobs, BH Salisbury, JM Terrell - 2018 - europepmc.org
Objectives: Identify the mechanism of action of aliskiren. Describe the potential adverse
effects of aliskiren. Summarize the place aliskiren can have in hypertension management …

Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and …

M Xu, W Zhai, Y Zhang, J Pan, J Li, S Huang - … Medicine and Therapies, 2023 - Springer
Abstract Background Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-
ni-san, is a highly effective formula with demonstrated efficacy in preventing depression in …

Difficulties in Treatment and Drug Selection in Patients With Arterial Hypertension With Renal Failure

T Larsson - 2023 - search.proquest.com
Objectives: 1. How to use combination of anti-hypertensive medication for patients with renal
failure. 2. The importance of lifestyle modification in antihypertensive therapy in patients with …

[PDF][PDF] Toivo Larsson

Toivo Larsson Page 1 LITHUANIAN UNIVERSITY OF HEALTH SCIENCES MEDICAL
ACADEMY INTERNAL MEDICINE DEPARTMENT Toivo Larsson DIFFICULTIES IN …

[HTML][HTML] Continuing Education Activity

TF Jacobs, BH Salisbury, JM Terrell - europepmc.org
Objectives: Identify the mechanism of action of aliskiren. Describe the potential adverse
effects of aliskiren. Summarize the place aliskiren can have in hypertension management …