Mechanisms and clinical relevance of bacterial heteroresistance
Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains
subpopulations of cells that show a substantial reduction in antibiotic susceptibility …
subpopulations of cells that show a substantial reduction in antibiotic susceptibility …
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed
from a research tool to a clinical application for the diagnosis and management of …
from a research tool to a clinical application for the diagnosis and management of …
Application of next generation sequencing for diagnosis and clinical management of drug-resistant tuberculosis: updates on recent developments in the field
N Dookie, A Khan, N Padayatchi, K Naidoo - Frontiers in Microbiology, 2022 - frontiersin.org
The World Health Organization's End TB Strategy prioritizes universal access to an early
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …
Best practices for evaluating single nucleotide variant calling methods for microbial genomics
Innovations in sequencing technologies have allowed biologists to make incredible
advances in understanding biological systems. As experience grows, researchers …
advances in understanding biological systems. As experience grows, researchers …
[HTML][HTML] Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential?
Background Nearly two decades after completion of the genome sequence of
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …
Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin
GR Davies, M Chaplin, M De Vos… - Cochrane Database …, 2022 - cochranelibrary.com
Background The World Health Organization (WHO) End TB Strategy stresses universal
access to drug susceptibility testing (DST). DST determines whether Mycobacterium …
access to drug susceptibility testing (DST). DST determines whether Mycobacterium …
Mapping and comparing bacterial microbiota in the sinonasal cavity of healthy, allergic rhinitis, and chronic rhinosinusitis subjects
Background The role of microbiota in sinonasal inflammation can be further understood by
targeted sampling of healthy and diseased subjects. We compared the microbiota of the …
targeted sampling of healthy and diseased subjects. We compared the microbiota of the …
[PDF][PDF] Optimized broth microdilution plate methodology for drug susceptibility testing of Mycobacterium tuberculosis complex
World Health Organization - 2022 - apps.who.int
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commercial purposes, provided the work is appropriately cited, as indicated below. In any …
commercial purposes, provided the work is appropriately cited, as indicated below. In any …
Whole-genome and targeted sequencing of drug-resistant Mycobacterium tuberculosis on the iSeq100 and MiSeq: A performance, ease-of-use, and cost evaluation
Background Accurate, comprehensive, and timely detection of drug-resistant tuberculosis
(TB) is essential to inform patient treatment and enable public health surveillance. This is …
(TB) is essential to inform patient treatment and enable public health surveillance. This is …