Viniferin is a resveratrol derivative. Resveratrol is the most prominent stilbenoid synthesized
by plants as a defense mechanism in response to microbial attack, toxins, infections or UV …

Neuroinflammation is a pathological feature of quite a number of Central Nervous System
diseases such as Alzheimer and Parkinson's disease among others. The hallmark of brain …

Noble rot results from exceptional infections of ripe grape (Vitis vinifera) berries by Botrytis
cinerea. Unlike bunch rot, noble rot promotes favorable changes in grape berries and the …

Convincing evidence has emerged demonstrating that impairment of mitochondrial function
is critically important in regulating alveolar epithelial cell (AEC) programmed cell death …

Grapevine canes are rich in resveratrol and its complex derivatives. These compounds have
many biological activities and are needed mainly for health purposes. Canes, which are …

Background Naturally occurring polyphenols found in food sources provide huge health
benefits. Several polyphenolic compounds are implicated in the prevention of disease …

Viticulture activity produces a significant amount of grapevine woody byproducts, such as
bunch stems and canes, which constitute potential sources of a wide range of phenolic …

Sirtuins (SIRTs) were originally characterized by yeast Sir2 as a lifespan regulator that is
conserved in all three structural domains of bacteria, archaea and eukaryotes and belong to …

Grapevine woody by-products contain bioactive substances, mainly phenolic compounds
(PCs), whose beneficial health effects initially depends on their levels of intake and …

Due to the confirmed therapeutic potential of resveratrol (Rv) for eye diseases, namely its
powerful anti-angiogenic and antioxidant effects, this molecule must be studied more …