Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …

Galectins, which were first characterized in the mid-1970s, were assigned a role in the
recognition of endogenous ('self') carbohydrate ligands in embryogenesis, development and …

Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …

Gastrointestinal (GI) parasites, hookworms in particular, have evolved to cause minimal
harm to their hosts, allowing them to establish chronic infections. This is mediated by …

Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …

The hookworm Necator americanus is the predominant soil-transmitted human parasite.
Adult worms feed on blood in the small intestine, causing iron-deficiency anemia …

In the developed world, declining prevalence of some parasitic infections correlates with
increased incidence of allergic and autoimmune disorders. Moreover, experimental human …

The human liver fluke, Opisthorchis viverrini, infects millions of people throughout south-east
Asia and is a major cause of cholangiocarcinoma, or cancer of the bile ducts. The …