Decoding the role of miRNAs in multiple myeloma pathogenesis: a focus on signaling pathways
AM Yehia, EGE Elsakka, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
[HTML][HTML] miR-214 as a key hub that controls cancer networks: small player, multiple functions
MicroRNAs are short regulatory RNAs that are able to post-transcriptionally modulate gene
expression and that have crucial roles in the control of physiological and pathological …
expression and that have crucial roles in the control of physiological and pathological …
Prognostic role of circulating exosomal miRNAs in multiple myeloma
Exosomes, secreted by several cell types, including cancer cells, can be isolated from the
peripheral blood and have been shown to be powerful markers of disease progression in …
peripheral blood and have been shown to be powerful markers of disease progression in …
Prediction of microRNAs Associated with Human Diseases Based on Weighted k Most Similar Neighbors
Background The identification of human disease-related microRNAs (disease miRNAs) is
important for further investigating their involvement in the pathogenesis of diseases. More …
important for further investigating their involvement in the pathogenesis of diseases. More …
[PDF][PDF] RETRACTED: downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
F Pichiorri, SS Suh, A Rocci, L De Luca, C Taccioli… - Cancer cell, 2010 - cell.com
In multiple myeloma (MM), an incurable B cell neoplasm, mutation or deletion of p53 is
rarely detected at diagnosis. Using small-molecule inhibitors of MDM2, we provide evidence …
rarely detected at diagnosis. Using small-molecule inhibitors of MDM2, we provide evidence …
miRSystem: an integrated system for characterizing enriched functions and pathways of microRNA targets
Background Many prediction tools for microRNA (miRNA) targets have been developed, but
inconsistent predictions were observed across multiple algorithms, which can make further …
inconsistent predictions were observed across multiple algorithms, which can make further …
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
Events mediating transformation from the pre-malignant monoclonal gammopathy of
undetermined significance (MGUS) to multiple myeloma (MM) are unknown. We analyzed …
undetermined significance (MGUS) to multiple myeloma (MM) are unknown. We analyzed …
Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma
Y Hu, J Lin, H Fang, J Fang, C Li, W Chen, S Liu… - Leukemia, 2018 - nature.com
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a highly conserved
long non-coding RNA (lncRNA). Overexpression of MALAT1 has been demonstrated to …
long non-coding RNA (lncRNA). Overexpression of MALAT1 has been demonstrated to …
[HTML][HTML] microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers
MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …
LncRNA NEAT1 sponges miR-214 to regulate M2 macrophage polarization by regulation of B7-H3 in multiple myeloma
Y Gao, P Fang, WJ Li, J Zhang, GP Wang, DF Jiang… - Molecular …, 2020 - Elsevier
Background LncRNA NEAT1 was associated with the tumorigenesis of multiple myeloma
(MM). However, the mechanisms of M2 macrophage polarization involved with NEAT1 in …
(MM). However, the mechanisms of M2 macrophage polarization involved with NEAT1 in …