[HTML][HTML] Pyrazole and pyrazoline derivatives as antimalarial agents: A key review

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Promising Schiff bases in antiviral drug design and discovery

S Kaushik, SK Paliwal, MR Iyer, VM Patil - Medicinal Chemistry Research, 2023 - Springer
Emerging and re-emerging illnesses will probably present a new hazard of infectious
diseases and have fostered the urge to research new antiviral agents. Most of the antiviral …

Design, synthesis, DNA binding, modeling, anticancer studies and DFT calculations of Schiff bases tethering benzothiazole-1, 2, 3-triazole conjugates

MA Almehmadi, A Aljuhani, SY Alraqa, I Ali… - Journal of Molecular …, 2021 - Elsevier
In an attempt to design and prepare a new library of anticancer candidates, focused
thiopropargylated benzothiazole was reacted with ethyl azidoacetate and/or ethyl …

Exploring the novel aryltellurium (IV) complexes: Synthesis, characterization, antioxidant, antimicrobial, antimalarial, theoretical and ADMET studies

M Dalal, N Antil, B Kumar, J Devi, S Garg - Inorganic Chemistry …, 2024 - Elsevier
The current research study is focused on biological efficacy of newly synthesized Schiff base
ligand 1, 1′-(ethane-1, 2-diylbis (azanylylidene)) bis (methanylylidene)) bis (naphthalen-2 …

Organyltellurium (IV) complexes incorporating Schiff base ligand derived from 2-hydroxy-1-naphthaldehyde: Preparation, spectroscopic investigations, antimicrobial …

M Dalal, A Dubey, A Tufail, N Antil, N Sehrawat… - Journal of Molecular …, 2023 - Elsevier
In this article, the synthesis of 1-(((2-nitrophenyl) imino) methyl) naphthalen-2-ol (H2NA)
Schiff base and its organyltellurium (IV) complexes were carried out and investigated via …

Discovery of new Schiff bases tethered pyrazole moiety: Design, synthesis, biological evaluation, and molecular docking study as dual targeting DHFR/DNA gyrase …

AS Hassan, AA Askar, AM Naglah, AA Almehizia… - Molecules, 2020 - mdpi.com
A series of Bis-pyrazole Schiff bases (6a–d and 7a–d) and mono-pyrazole Schiff bases (8a–
d and 9a–d) were designed and synthesized through the reaction of 5-aminopyrazoles 1a–d …

Synthesis of novel pyrazolone candidates with studying some biological activities and in-silico studies

MH Abdellattif, EO Hamed, NKR Elhoseni, MG Assy… - Scientific reports, 2023 - nature.com
Pyranopyrazole derivatives have a vital role in the class of organic compounds because of
their broad spectrum of biological and pharmacological importance. Our current goal is the …

Exploring the antimicrobial, antioxidant and cytotoxic activities of organyltellurium (IV) complexes incorporating 2‐hydroxy‐1‐naphthaldehyde schiff base ligand …

M Dalal, J Devi, N Antil, B Kumar… - Applied …, 2024 - Wiley Online Library
In this study, Schiff base ligand 1, 1′‐((propane‐1, 3‐diylbis azaneylylidene) bis
(methaneylylidene)) bis (naphthalen‐2‐ol) based Organyltellurium (IV) complexes were …

Recent insights into antibacterial potential of benzothiazole derivatives

P Kashyap, S Verma, P Gupta, R Narang, S Lal… - Medicinal Chemistry …, 2023 - Springer
Antimicrobial resistance (AMR) is a worldwide concern among infectious diseases due to
increased mortality, morbidity and treatment cost. According to WHO 2019 report, among the …

A review of antimalarial activity of two or three nitrogen atoms containing heterocyclic compounds

A Chugh, A Kumar, A Verma, S Kumar… - Medicinal Chemistry …, 2020 - Springer
Malaria, a nocuous disease, which has become a major challenge for the health resulting in
deaths of millions of people around the globe. Malaria is a parasitic disease propagated by …