Pain and pain chronification are incompletely understood and unresolved medical problems
that continue to have a high prevalence. 14 It has been accepted that pain is a complex …

Introduction Artificial intelligence (AI) is a field of mathematical engineering which has
potential to enhance healthcare through new care delivery strategies, informed decision …

Patients with fibromyalgia (FM) show characteristically enhanced unpleasantness to painful
and nonpainful sensations accompanied by altered neural responses. The diagnostic …

Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …

This go-to manual--now revised and significantly expanded with more than 50% new
material--has enabled thousands of clinicians to effectively treat clients with chronic pain. In …

Background: Traditional pain assessment methods have significant limitations due to the
high variability in patient reported pain scores and perception of pain by different individuals …

A relatively large number of studies have investigated the power of structural magnetic
resonance imaging (sMRI) data to discriminate patients with schizophrenia from healthy …

Currently, the development of medicines for complex diseases requires the development of
combination drug therapies. It is necessary because in many cases, one drug cannot target …

Background Pain and substance use are frequently comorbid and have been shown to exert
bidirectional effects. Self-medication of pain and distress via substance use is common and …

Chronic pain is known as a complex disease due to its comorbidities with other symptoms
and the lack of effective treatments. As a consequence, chronic pain seems to be under …