Molecular mechanisms influencing efficiency of RNA interference in insects

AMW Cooper, K Silver, J Zhang, Y Park… - Pest management …, 2019 - Wiley Online Library
RNA interference (RNAi) is an endogenous, sequence‐specific gene‐silencing mechanism
elicited by small RNA molecules. RNAi is a powerful reverse genetic tool, and is currently …

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

SE Castel, RA Martienssen - Nature Reviews Genetics, 2013 - nature.com
A growing number of functions are emerging for RNA interference (RNAi) in the nucleus, in
addition to well-characterized roles in post-transcriptional gene silencing in the cytoplasm …

Nematode effector proteins: an emerging paradigm of parasitism

MG Mitchum, RS Hussey, TJ Baum, X Wang… - New …, 2013 - Wiley Online Library
Phytonematodes use a stylet and secreted effectors to modify host cells and ingest nutrients
to support their growth and development. The molecular function of nematode effectors is …

The genome and life-stage specific transcriptomes of Globodera pallidaelucidate key aspects of plant parasitism by a cyst nematode

JA Cotton, CJ Lilley, LM Jones, T Kikuchi, AJ Reid… - Genome biology, 2014 - Springer
Background Globodera pallida is a devastating pathogen of potato crops, making it one of
the most economically important plant parasitic nematodes. It is also an important model for …

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

EM Schwarz, PK Korhonen, BE Campbell, ND Young… - Genome biology, 2013 - Springer
Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …

Key mechanistic principles and considerations concerning RNA interference

P Svoboda - Frontiers in plant science, 2020 - frontiersin.org
Canonical RNAi, one of the so-called RNA-silencing mechanisms, is defined as sequence-
specific RNA degradation induced by long double-stranded RNA (dsRNA). RNAi occurs in …

Implementation of RNAi-based arthropod pest control: environmental risks, potential for resistance and regulatory considerations

O Christiaens, J Sweet, T Dzhambazova, I Urru… - Journal of Pest …, 2022 - Springer
Just over 20 years since the RNA interference (RNAi) mechanism was unraveled in the
nematode Caenorhabditis elegans, the first RNAi-based pest control applications are close …

Genetic blueprint of the zoonotic pathogen Toxocara canis

XQ Zhu, PK Korhonen, H Cai, ND Young… - Nature …, 2015 - nature.com
Toxocara canis is a zoonotic parasite of major socioeconomic importance worldwide. In
humans, this nematode causes disease (toxocariasis) mainly in the under-privileged …

Molecular biology of root lesion nematodes (Pratylenchus spp.) and their interaction with host plants

MGK Jones, J Fosu‐Nyarko - Annals of applied biology, 2014 - Wiley Online Library
Plant‐parasitic nematodes of the genus Pratylenchus are among the top three most
significant nematode pests of crop and horticultural plants worldwide. There are more than …

RNA interference in plant parasitic nematodes: a summary of the current status

CJ Lilley, LJ Davies, PE Urwin - Parasitology, 2012 - cambridge.org
RNA interference (RNAi) has emerged as an invaluable gene-silencing tool for functional
analysis in a wide variety of organisms, particularly the free-living model nematode …