Mid–Long Chain Dicarboxylic Acid Production via Systems Metabolic Engineering: Progress and Prospects

S Gu, F Zhu, L Zhang, J Wen - Journal of Agricultural and Food …, 2024 - ACS Publications
Mid-to-long-chain dicarboxylic acids (DCA i, i≥ 6) are organic compounds in which two
carboxylic acid functional groups are present at the terminal position of the carbon chain …

The potential of native and engineered Clostridia for biomass biorefining

P Ponsetto, EM Sasal, R Mazzoli, F Valetti… - … in Bioengineering and …, 2024 - frontiersin.org
Since their first industrial application in the acetone-butanol-ethanol (ABE) fermentation in
the early 1900s, Clostridia have found large application in biomass biorefining. Overall, their …

The role of AdhE on ethanol tolerance and production in Clostridium thermocellum

A Pech-Canul, SK Hammer, SJ Ziegler… - Journal of Biological …, 2024 - jbc.org
Many anaerobic microorganisms use the bifunctional aldehyde and alcohol dehydrogenase
enzyme, AdhE, to produce ethanol. One such organism is Clostridium thermocellum, which …

Adaptive laboratory evolution of Thermoanaerobacterium aotearoense for enhanced ethanol production from raw cassava starch

K Dai, Y Miao, C Qu, C Wang, H Fu, J Wang - Renewable Energy, 2024 - Elsevier
Thermophiles have the potential to utilize starch for bioethanol production in consolidated
bioprocessing procedure, but they are usually limited by the intolerance of high ethanol titer …

[HTML][HTML] Expression and Characterization of Monofunctional Alcohol Dehydrogenase Enzymes in Clostridium thermocellum

DP Chiarelli, BD Sharma, S Hon, LW Bergamo… - Metabolic Engineering …, 2024 - Elsevier
Clostridium thermocellum is a thermophilic anaerobic bacterium that could be used for
cellulosic biofuel production due to its strong native ability to consume cellulose, however its …

Adaptive evolution of Clostridium thermocellum ATCC 27405 on alternate carbon sources leads to altered fermentation profiles

SR Daley, S Kirby, R Sparling - Canadian Journal of …, 2024 - cdnsciencepub.com
Consolidated bioprocessing candidate, Clostridium thermocellum, is a cellulose hydrolysis
specialist, with the ability to ferment the released sugars to produce bioethanol. C …

[HTML][HTML] Pyrophosphate-free glycolysis in Clostridium thermocellum increases both thermodynamic driving force and ethanol titers

BD Sharma, S Hon, E Thusoo… - … for Biofuels and …, 2024 - pmc.ncbi.nlm.nih.gov
Background Clostridium thermocellum is a promising candidate for production of cellulosic
biofuels, however, its final product titer is too low for commercial application, and this may be …

Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum: A containment strategy for toxic intermediates

SJ Ziegler, BC Knott, JN Gruber, NN Hengge, Q Xu… - bioRxiv, 2024 - biorxiv.org
Clostridium thermocellum, a cellulolytic thermophilic anaerobe, is considered by many to be
a prime candidate for the realization of consolidated bioprocessing (CBP) and is known as …