Elucidating protein–protein interaction (PPI) networks and their structural features within
cells is central to understanding fundamental biology and associations of cell phenotypes …

Chemical reagents with special groups as enrichable handles have empowered the ability
to label and enrich modified peptides. Here is an overview of different chemical reagents …

Protein dynamics play a crucial role in their diverse functions. The intracellular environment
significantly influences protein dynamics, particularly for intrinsically disordered proteins …

Structural information on protein–protein interactions (PPIs) is essential for improved
understanding of regulatory interactome networks that confer various physiological and …

Unlocking the intricacies of protein structures and interactions within the dynamic landscape
of subcellular organelles presents a significant challenge. To address this, we introduce …

Protein–protein interactions (PPIs) are fundamental to understanding biological systems as
protein complexes are the active molecular modules critical for carrying out cellular …

The validity of protein structures and interactions, whether determined under ideal laboratory
conditions or predicted by AI tools such as Alphafold2, to precisely reflect those found in …

Cross-linking mass spectrometry (XL-MS) is a powerful technology that recently emerged as
an essential complementary tool for elucidating protein structures and mapping interactions …

Cross-linking mass spectrometry (XL-MS) is a powerful technology for mapping protein-
protein interactions (PPIs) at the systems-level. By covalently connecting pairs of proximal …